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Laser path

XRCC1. PARP-2. Lig3. Polß. PARP-1. APTX. NLS. BRCT 2. BRCT 1. E. D. 1. 183. 314. 371. 538. 633. PNK. hOGG1. APE1. TdP1. PCNA. Laser path. The recruitment of GFP-XRCC1 mediated by its BRCT1 module occurs within 10-20 seconds at DNA breaks-induced poly(ADP-ribose) foci.

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Laser path

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  1. XRCC1 PARP-2 Lig3 Polß PARP-1 APTX NLS BRCT 2 BRCT 1 E D 1 183 314 371 538 633 PNK hOGG1 APE1 TdP1 PCNA Laser path The recruitment of GFP-XRCC1 mediated by its BRCT1 module occurs within 10-20 seconds at DNA breaks-induced poly(ADP-ribose) foci Spenlehauer et al. (in press)

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