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PneumoniaCheck

PneumoniaCheck. David N. Ku, MD, PhD Regents ’ Professor and L.P. Huang Chair Prof Engineering Entrepreneurship Larry Anderson, Jonas Wenchel - CDC. Georgia Institute of Technology Disclosure: Company ownership. Pneumonia. Infection of the lungs #1 cause of death in children worldwide.

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PneumoniaCheck

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  1. PneumoniaCheck David N. Ku, MD, PhD Regents’ Professor and L.P. Huang Chair Prof Engineering Entrepreneurship Larry Anderson, Jonas Wenchel - CDC Georgia Institute of Technology Disclosure: Company ownership

  2. Pneumonia Infection of the lungs #1 cause of death in children worldwide

  3. Current situation • Pneumonia kills1,000 children daily in rural India • Limited availability and accessibility of diagnostics • 80% undiagnosed with current methods

  4. Gates Foundation • Grand Challenge • Pneumonia • TB - Tuberculosis • LRTI – Lower Respiratory Tract Infection • Airborne contagious disease • SuperSpreaders

  5. Problem - Sampling • Current diagnosis uses mouth and nose samples • Normal mouths have pneumococcus • Specimens contaminated • Many false positives

  6. Bronchoalveolar Lavage (BAL) Current method to get a lung sample Isolated treatment for antibiotic therapy

  7. Solution - PneumoniaCheck™ PneumoniaCheck™ uses fluid mechanics to isolate lung pathogens onto filter

  8. Solution - PneumoniaCheck™

  9. Solution - PneumoniaCheck™

  10. Solution - PneumoniaCheck™

  11. Analysis • Microbiology- Traditional culture methods • DNA Polymerase Chain Reaction (PCR)- Highly sensitive- Identifies multiple pathogens simultaneously- Rapid turnaround (<24 hours)

  12. Huge unaddressed market • Patent pending, disruptive technology • Good Manufacturing Practices - FDA cleared medical device • Expanding indications • Distribution and Sales

  13. Addressable Market Size Target hospitals, make standard Florida 105,000 Cases $10.5 million United States 5,600,000 cases $560 million Atlanta 9,500 Cases $900,000 Texas 110,000 Cases $11 million http://www.ahd.com/state_statistics.html

  14. Better Medicine: • PneumoniaCheck™ selectively collects from lungs • Broad-spectrum antibiotics reduced • Hospital stay shortened, less complications • Save approximately $1,000 per patient • Triple Bottom Line Company

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