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Syphilis: The Great Pox

Syphilis: The Great Pox. Jordan Best. Syphilis is caused by an infection of the bacteria Treponema pallidum. T. pallidum rapidly enters the bloodstream and becomes systemic. Primary Syphilis involves formation of “chancres” at site of infection.

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Syphilis: The Great Pox

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  1. Syphilis: The Great Pox Jordan Best

  2. Syphilis is caused by an infection of the bacteria Treponemapallidum

  3. T. pallidum rapidly enters the bloodstream and becomes systemic

  4. Primary Syphilis involves formation of “chancres” at site of infection

  5. Secondary Syphilis is characterized by lesions of mucous membranes and skin

  6. Latent Stage Syphilis can remain asymptomatic for decades

  7. Tertiary Syphilis adversely affects a wide variety of tissue and can be debilitating or fatal • Brain, heart, nervous system, liver, eyes, vascular system

  8. In early stages, the disease is easily cured with a single intramuscular antibiotic injection

  9. Azithromycin-resistant strains began to appear in the late 1990’s.

  10. Developing nations are especially afflicted by syphilis

  11. One of the few diseases to spread to Europe from the New World

  12. Many historical figures died from syphilis • Christopher Columbus • Napoleon Bonaparte • Al Capone • King Henry VIII

  13. References • http://www.who.int/reproductivehealth/topics/rtis/syphilis/en/index.html • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225993/ • http://www.who.int/std_diagnostics/publications/Disease%20watch%20syphilis.pdf • http://www.ncbi.nlm.nih.gov/pubmed/16392078

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