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Risk factors for Candidiasis. General Conditions causing a compromised host defense Neutropenia Glucocorticoid therapy Malnutrition. Risk factors for Candidiasis. Oropharyngeal thrush Diabetes mellitus HIV infection Common in acute HIV infection
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Risk factors for Candidiasis • General • Conditions causing a compromised host defense • Neutropenia • Glucocorticoid therapy • Malnutrition Reference: http://www.harrisonspractice.com/practice/ub/view/Harrisons%20Practice/141100/0/Candida
Risk factors for Candidiasis • Oropharyngeal thrush • Diabetes mellitus • HIV infection • Common in acute HIV infection • Increasingly common late in disease as the CD4+ cell count falls • Dentures • Inhaled or oral glucocorticoids • Neonatal period • Iron deficiency Reference: http://www.harrisonspractice.com/practice/ub/view/Harrisons%20Practice/141100/0/Candida
Risk factors for Candidiasis • Vulvovaginalcandidiasis • Third trimester of pregnancy • Antibiotic use Reference: http://www.harrisonspractice.com/practice/ub/view/Harrisons%20Practice/141100/0/Candida
Risk factors for Candidiasis • Cutaneouscandidiasis • Macerated skin • Diapered area of infants • Under pendulous breasts or pannus • Hands constantly in water • Hands covered by occlusive gloves Reference: http://www.harrisonspractice.com/practice/ub/view/Harrisons%20Practice/141100/0/Candida
Risk factors for Candidiasis • Esophageal candidiasis • HIV infection • Uncommon until CD4+ counts fall below 50/μL Reference: http://www.harrisonspractice.com/practice/ub/view/Harrisons%20Practice/141100/0/Candida
Risk factors for Candidiasis • Invasive candidiasis • Use of broad-spectrum antibiotic therapy • Indwelling central venous catheter • Total parenteral nutrition • Perforation of the GI tract through trauma, surgery, or peptic ulceration • Mucosal damage due to cytotoxic agents used for cancer chemotherapy • Contamination of the hub or skin site of a catheter in an umbilical or central vein with secretions from the mouth, rectum, or vagina or with drainage from surgical wounds or tracheostomy sites • Intravenous drug abuse • Third-degree burns • Very low birth weight (in neonates) • Neutropenia • Glucocorticoid therapy Reference: http://www.harrisonspractice.com/practice/ub/view/Harrisons%20Practice/141100/0/Candida