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Pregnancy and Epilepsy

Pregnancy and Epilepsy.  Most pregnancies in mothers with epilepsy produce normal children  Fetal anomalies (up to 10% of pregnancies) are multifactorial Drug effects Consequences of the mother’s underlying diseases Consequence of maternal seizures during pregnancy

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Pregnancy and Epilepsy

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  1. Pregnancy and Epilepsy  Most pregnancies in mothers with epilepsy produce normal children  Fetal anomalies (up to 10% of pregnancies) are multifactorial • Drug effects • Consequences of the mother’s underlying diseases • Consequence of maternal seizures during pregnancy  All antiepileptic drugs carry teratogenic risks  Polytherapy increases risk Reference: Practice Parameter: Management issues for women with epilepsy (summary statement): Report of the Quality of Standards Subcommittee of the American Academy of Neurology. Neurology 1998; 51: 944-948.

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