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Chulabhorn Graduate Institute Environmental Toxicology Program. Program Management Committee. Assoc. Prof. Dr. Jutamaad Satayavivad. Chairperson. Program Management Committee. Dr. Panida Navasumrit. Dr. Daam Settachan. Dr. Piyajit Watcharasit. Dr. Nuchanart Rangkadilok.
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ChulabhornGraduate Institute Environmental Toxicology Program
Program Management Committee Assoc. Prof. Dr. JutamaadSatayavivad Chairperson
Program Management Committee Dr. PanidaNavasumrit Dr. Daam Settachan Dr. PiyajitWatcharasit Dr. NuchanartRangkadilok Dr. JantamasKanitwithayanun
ET Curriculum - credits * Basic science (3) + Environmental Toxicology (9) = 12
ET Curriculum – core courses • Principles of Toxicology (3 credits) • Environmental Toxicology (2 credits) • Seminar in Environmental Toxicology (2 credits) • Environmental and Health Risk Assessment and Management of Toxic Chemicals (2 credits) • Detection of Environmental Pollutants and Monitoring of Health Effects (3 credits)
Nature of Courses/Teaching Traditional lectures – highly technical, i.e. mechanistic: Principles of Toxicology; Immunotoxicology & Reproductive Toxicology; Environmental Toxicology Lectures with practical component: Detection of Environmental Pollutants and Monitoring of Health Effects Lectures that include policy components: Environmental and Health Risk Assessment and Management of Toxic Chemicals; Health, Development & Environment Others: - Seminar in Environmental Toxicology - Case Studies in Applied Biosciences
ET Research Goals • Elucidate mechanisms through which chemical, physical &biological agents in the environment induce toxicity &pathogenesis, including cancer • Understand effects of environmental pollutants &industrial chemicals as modifiers of physiological &pathological status, & influence of host factors such as nutritional status & disease states on toxicity &carcinogenicity of chemicals • Develop new methods for detection of environmental toxicants • Understand gene-environment interactions
Examples of ET Research • Exposure &health impacts of urban air pollution, particularly carcinogenic compounds such as PAHs, benzene and 1,3-butadiene • Cellular responses to chronic arsenic exposure in Southern Thailand • Effects of vitamin B deficiency on toxicity of benzene • Biomarkers of exposure, effects &susceptibility in environmentally & occupationally exposed people • Detection of environmental toxicants by dielectrophoresis
CB, ABS & ET • ET is relatively narrow in focus - measuring exposures and effects, & understanding mechanisms of action & modifying factors • ABS focuses on disease & covers other factors, including influence of environmental factors, e.g. climate change, etc… • Drug development pulls all programs together – understanding target disease (ABS) to drug discovery (CB) to drug testing (ET)
Applied Biological Sciences: Environmental Health Chemical Biology Environmental Toxicology • MS PhD • Core: 1515 • Elective: 9 9 • Thesis: 1236 • Total: 3660 • Principles of Applied Biosciences • Experimental Strategies for Biological Problems • Case Studies in Applied Biosciences • Advanced Organic Chemistry • Spectroscopic Methods for Organic Compounds & Biomolecules • Drug Discovery & Development • MS PhD • Core: 1313 • Elective: 1111 • Thesis: 1236 • Total: 3660 • Principles of Applied Biosciences • Experimental Strategies for Biological Problems • Case Studies in Applied Biosciences • Pathobiology & Analysis of Disease at the Organism Level • Pathobiology & Analysis of Disease at the Population Level • MSPhD • Core: 912 • Elective: 1512 • Thesis: 1236 • Total: 36 60 • Principles of Toxicology • Environmental Toxicology • Seminar in Environmental Toxicology • Detection of Environmental Pollutants & Monitoring of Health Effects • Environmental & Health Risk Assessment & Management