Gene Expression in End-Stage Dilated Cardiomyopathy

Jul 21, 2013

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Gene Expression in End-Stage Dilated Cardiomyopathy

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IDIOPATHIC DILATED CARDIOMYOPATHY

IDIOPATHIC DILATED CARDIOMYOPATHY. NEW INSIGHTS INTO PATHOGENESIS AND TREATMENT Dartmouth-Hitchcock Medical Center April 2004. ETIOLOGIES OF DILATED CARDIOMYOPATHY. Felker et al NEJM 2000. IDIOPATHIC DILATED CARDIOMYOPATHY PATHOLOGY. Four chamber dilatation

1.4k views • 51 slides

Gene Expression

Gene Expression. Gene expression?. Biological processes, such as transcription, and in case of proteins, also translation, that yield a gene product. A gene is expressed when its biological product is present and active. Gene expression is regulated at multiple levels.

643 views • 32 slides

Viral Myocarditis and Dilated Cardiomyopathy

E d. Viral Myocarditis and Dilated Cardiomyopathy. Kristine Scruggs, MD AM Report 10 March 2010. Signs & Symptoms of Myocarditis. Excessive fatigue Chest pain Unexplained sinus tachycardia Acute pericarditis S3, S4 or summation gallop Abnormal electrocardiogram

912 views • 10 slides

Gene Expression

Gene Expression. The human genome contains about 20,325 protein-encoding genes - However, this represents only a small part of the genome Much of the human genome controls protein synthesis - Including the time, speed, and location. Proteins have diverse functions in the body.

809 views • 59 slides

Two Stage Processes of Gene Expression

Two Stage Processes of Gene Expression. Transcription: - mRNA - tRNA - rRNA. Translation: - mRNA translated to Protein - tRNA & rRNA provide other components of the apparatus for protein synthesis. Prokaryotic Translation. Life Cycle of mRNA. Fig5.19 Two stage process of

396 views • 28 slides

Gene Expression

Gene Expression. Gene: contains the recipe for a protein. 1. is a specific region of DNA on a chromosome. 2. codes for a specific mRNA. mRNA: exits the nucleus and associates with ribosomes. 1. carries the code for a specific protein to the cytoplasm.

435 views • 26 slides

Gene Expression

Gene Expression. 1: Activation (overview), Transcription, Translation.  The Goodwin Equations. Review. An active gene is one that is being transcribed , and whose transcription product is being translated , and whose translation product affects cellular behavior/development.

649 views • 38 slides

Gene Expression

Gene Expression. Review covering RNA Processing & Translation. Posttranscriptional ( RNA Processing). - Transcription has created a primary transcript (pre mRNA) that is not ready to be exported from the nucleus to the ribosome in the cytosol.

388 views • 21 slides

Cardiomyopathy, End-stage Heart Disease & Transplantation

Cardiomyopathy, End-stage Heart Disease & Transplantation. Seoul National University Hospital Department of Thoracic & Cardiovascular Surgery. Hypertrophic Cardiomyopathy. Hypertrophic Cardiomyopathy. Definition

1.23k views • 97 slides

Molecular basis of dilated cardiomyopathy

Molecular basis of dilated cardiomyopathy. Prasad Gunaruwan 21 st June 2011. Introduction. Didactic, regular questions to the audience Pathology of dilated cardiomyopathy Myocyte apoptosis, regulators Structure of the cardiac myocyte Inherited DCM and mechanisms

788 views • 42 slides

GENE EXPRESSION

GENE EXPRESSION. First genes must become AVAILABLE for expression. There are ROAD BLOCKS to becoming available. Exs . Does the cell have the needed DNA sequence?

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Sarcomeric Protein Mutations in Dilated Cardiomyopathy

Sarcomeric Protein Mutations in Dilated Cardiomyopathy. DCM. A heart disease characterized by dilatation and impaired contraction of the left ventricle or both ventricles. A relatively common disease, affecting about 36.5 out of 100,000 people, of which, 25–30% are familial DCM.

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Gene expression

Gene expression. Transcription and Translation. 1. Important Features. a. DNA contains genetic template for proteins. b. DNA is found in the nucleus c. Protein synthesis occurs in the cytoplasm - ribosome.

497 views • 32 slides

Gene Expression

Gene Expression. Early evidence indicating most genes specify the structure of proteins Garrod’s work on inborn errors of metabolism in early 1900s Beadle and Tatum’s work with Neurospora mutants in the 1940s. An “inborn error of metabolism”. Mutations affecting biochemical pathways.

465 views • 24 slides

Aarkstore - Dilated Cardiomyopathy - Pipeline Review, H2 201

“Dilated Cardiomyopathy - Pipeline Review, H2 2014”, provides an overview of the Dilated Cardiomyopathys therapeutic pipeline. For more details : http://goo.gl/HxMXnF

503 views • 11 slides

Gene Expression

Gene Expression. How proteins are made. W O R K T O G E T H E R. what monomers make up proteins? what monomers make up nucleic acids (DNA and RNA)?. Nucleic Acids. Proteins. Primarily ___ , ___. _________ of different proteins. Made up of ____ different bases.

467 views • 41 slides

Gene Expression

Gene Expression. How proteins are made. W O R K T O G E T H E R. what monomers make up proteins? what monomers make up nucleic acids (DNA and RNA)?. Nucleic Acids. Proteins. Primarily DNA , RNA. Thousands of different proteins. Made up of four different bases.

610 views • 56 slides

Gene Expression

Gene Expression. Chapter 17: From Gene to Protein. The Central Dogma of Biology. DNA (in genes) is a recipe book for polypeptides (proteins) RNA is an essential partner in this process Proteins are the links between genotype and phenotype

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Dilated Cardiomyopathy Market

The total prevalent cases of Dilated Cardiomyopathy in the 7MM are expected to be 2,523,808 in 2020. The Dilated Cardiomyopathy market is expected to grow with a CAGR of 13.1% in the 7MM during the study period (2017u20132030). Increasing prevalence rate, increased healthcare spending, and emerging treatment options are some of the key factors expected to drive the Dilated Cardiomyopathy market in the upcoming years. The key players in the Dilated Cardiomyopathy market include Pfizer, MyoKardia, Capricor Therapeutics, Vericel Corporation, Berlin Cures, Cumberland Pharmaceuticals and many others. For more details visit: https://www.delveinsight.com/report-store/dilated-cardiomyopathy-dcm-market-insights

46 views • 1 slides

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Gene Expression in End-Stage Dilated Cardiomyopathy

Gene Expression in End-Stage Dilated Cardiomyopathy

Presentation Transcript

IDIOPATHIC DILATED CARDIOMYOPATHY

Gene Expression

Viral Myocarditis and Dilated Cardiomyopathy

Gene Expression

Two Stage Processes of Gene Expression

Gene Expression

Gene Expression

Gene Expression

Cardiomyopathy, End-stage Heart Disease &amp; Transplantation

Molecular basis of dilated cardiomyopathy

GENE EXPRESSION

Sarcomeric Protein Mutations in Dilated Cardiomyopathy

Gene expression

Gene Expression

Aarkstore - Dilated Cardiomyopathy - Pipeline Review, H2 201

Gene Expression

Gene Expression

Gene Expression

Dilated Cardiomyopathy Market

Cardiomyopathy, End-stage Heart Disease & Transplantation