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Analgesics

Analgesics. By: Ravi Gaddipati. Assessment Statements. D.3.1 Describe the different ways analgesics prevent pain D.3.2 Describe the use of derivatives of salicylic acid as mild analgesics and compare the pros and cons of using aspirin and paracetamol

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Analgesics

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  1. Analgesics By: Ravi Gaddipati

  2. Assessment Statements • D.3.1 Describe the different ways analgesics prevent pain • D.3.2 Describe the use of derivatives of salicylic acid as mild analgesics and compare the pros and cons of using aspirin and paracetamol • D.3.3 Compare the structure of morphine, codeine and diamorphine (heroin, a semi-synthetic opiate) • D.3.4 Discuss the advantages and disadvantages of using morphine and its derivatives as strong analgesics

  3. D.3.1 Describe the different ways analgesics prevent pain

  4. D.3.2 Describe the use of derivatives of salicylic acid as mild analgesics and compare the pros and cons of using aspirin and paracetamol • Salicylic acid reacts to form aspirin in a condensation reaction: • C₇H₆O₃ + C₄H₆O₃ → C₉H₈O₄ + C₂H₄O₂ • Aspirin- minimizes blood clotting • Disadvantages • stomach bleeding • Asthma • Paracetamol- helps relieve pain. • Disadvantages • Overuse can possibly cause kidney/liver damage • negative effects also magnified by alcoholic consumption

  5. D.3.3 Compare the structure of morphine, codeine and diamorphine (heroin, a semi-synthetic opiate) • Heroin has 2 ester groups, a amine group, a benzene group, and a ether group • Codeine contains a hydroxy group, and amine group, and benzene group

  6. D.3.4 Discuss the advantages and disadvantages of using morphine and its derivatives as strong analgesics • Morphine: • Short Term: • Severe pain • Constipation • Long Term: • Dependence • Heroin • Good feeling • Tolerance • Additction • Constipation

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