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Glycerol Release and Response to Epinephrine and Isoproterenol in Phentolamine-Treated Subjects

This study examines the extracellular release of glycerol and the response to epinephrine and isoproterenol in subjects treated with phentolamine. Results show an increase in glycerol release and altered response to epinephrine and isoproterenol.

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Glycerol Release and Response to Epinephrine and Isoproterenol in Phentolamine-Treated Subjects

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  1. FIGURE 1 # * NS 1000 800 LFD HFD 600 Extracellular glycerol release (µM) 400 NS NS 200 0 - + - + - + - + Phentolamine Rest Exercice Rest Exercice

  2. FIGURE 2 n = 9 Day 0 A 3 * 2,5 * + RX 821002 2 Fold basal increased 1,5 1 0,5 -10 -9 -8 -7 -6 -5 -6 Log [Iso] (M) Log [epinephrine] (M) n = 9 Day 2 B 3 * 2,5 * + RX 821002 2 Fold basal increased 1,5 1 0,5 -10 -9 -8 -7 -6 -5 -6 Log [epinephrine] (M) Log [Iso] (M) C Day 2 + BrPal n = 9 3 2,5 + RX 821002 2 Fold basal increased 1,5 1 0,5 -10 -9 -8 -7 -6 -5 -6 Log [epinephrine] (M) Log [Iso] (M)

  3. TABLE 1

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