1 / 34

Filtration Barrier

Filtration Barrier. Lamina rara externa Lamina densa Lamina rara interna. Glomerular Filtration. Filtering of blood in the renal corpuscle Glomerular filtrate – fluid that seeps from the glomerular capillaries into the Bowman’s space. Renal Tubule. Proximal convoluted tubule

tarika
Download Presentation

Filtration Barrier

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Filtration Barrier • Lamina rara externa • Lamina densa • Lamina rara interna

  2. Glomerular Filtration • Filtering of blood in the renal corpuscle • Glomerular filtrate – fluid that seeps from the glomerular capillaries into the Bowman’s space

  3. Renal Tubule • Proximal convoluted tubule • Loop of Henle • Thick descending limb • Thin descending and ascending limbs • Thick ascending limb • Distal convoluted tubule • Collecting tubules and ducts

  4. Renal Tubule

  5. Types of Nephrons • Short-looped (cortical) - majority • Renal corpuscles located in outer portions of cortex • Short Henle’s loop (no thin ascending limb) • Long-looped (juxtamedullary) • Renal corpuscles are near the corticomedullary junction • Long Henle’s loop (go deep into medulla, have thin ascending limb)

  6. Juxtaglomerular Apparatus • Microscopic structure in the kidney which regulates the function of each nephron • Found between the vascular pole of the renal corpuscle and the returning DCT of the same nephron • Function: regulates filtrate formation and systemic BP

  7. Juxtaglomerular Apparatus • 3 cells: • Juxtaglomerular cells • Mesangial cells • Macula densa cells - area of closely packed specialized columnar cells lining the wall of the distal tubule • Sense changes in solute concentration and flow rate of filtrate

  8. BLADDER AND URINARY PASSAGES • Renal calyces • Renal pelvis • Ureter • Urinary bladder • Same histologic structure • Walls of ureter becoming gradually thicker as proximity to the bladder increases

  9. BLADDER AND URINARY PASSAGES • Function: • Store the urine formed in the kidneys and conduct it to the exterior

  10. BLADDER AND URINARY PASSAGES • Mucosa: • Transitional epithelium • Lamina propria: loose to dense CT • Muscular layer – OCIL • Adventitia or serosa • Only upper part of bladder covered by peritoneum

  11. URETHRA • Terminal portion of the urinary system • Function: • Passageway for urine • Males: passageway for urine and sperms

  12. Male Urethra • 20 cm in length • 3 segments: • Prostatic urethra • Membranous urethra • Spongy urethra (penile, cavernous) • Terminates in the external urethral orifice (meatus)

  13. Male Urethra

  14. Female Urethra • Shorter (4 cm) • Closely attached to anterior wall of vagina • Opens directly in front of the vaginal opening on the vestibule of the external genitalia

  15. Female Urethra

  16. Female Urethra • Mucosa • Transitional → stratified squamous non-keratinized • Lamina propria: loose CT, mucus-secreting urethral glands • Muscular layer: circularly arranged smooth muscle cells

  17. Female Urethra • Distal segment is surrounded by circularly-arranged striated (voluntary) muscle fibers (sphincter urethrae muscle – external sphincter)

More Related