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FL #14 Immune System 10BC. Figure 40–8 Structure of an Antibody. Section 40-2. Antigen- binding sites. Antigen. Antibody. bacterium. The bacterium is an antigen. An infectious disease is caused by. Pathogens Bacteria, viruses, & fungi (germs).
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Figure 40–8 Structure of an Antibody Section 40-2 Antigen-binding sites Antigen Antibody bacterium • The bacterium is an antigen
An infectious disease is caused by • Pathogens • Bacteria, viruses, & fungi (germs).
Antibodies-protein that helps destroy pathogens • Has 2 antigen binding sites • Pathogen invades body • Antigens on pathogen recognized by some B cells
Specific Defenses • A. Humoral immunity- • Immunity against pathogens in the body fluids (blood & lymph) • 1-B cells (WBC) lymphocyte-produce antibodies
Antigen/antibodies • 2- Activated B cells grow and divide rapidly (a million) • 3-Produce specialized B cells-plasma cells (T cells help with this also) • 4-Plasma cells-release antibodies into the blood to attack the pathogen causing infection
A person who receives a vaccine for the flu-influenza • Is able to produce antibodies against the flu
When a person receives a vaccine(shot) their body • create plasma cells (B cells) that can produce antibodies against a specific pathogen. (flu, polio, hepatitis)
Function of Antibodies: • Attach to antigens and attract phagocytes which engulf (eat) the antigens
phagocytes-engulf & destroy bacteria –most WBC are this type “phag”=eat, “cytes”=cell
Inflammatory Response • Pathogens detected • Millions of WBC’s produced to fight infection • Blood test reveals increase in WBC’s-body is dealing w/ a serious infection • Immune system releases chemicals that increase core temperature
FEVER- INCREASED body temp • Many pathogens survive in a narrow temp. range • Elevated temp:1) slows down or stops growth of pathogens • 2) increase heart rate, WBC’s get to infection quicker • 3)Speeds activities of WBC’s & rate of chemical reactions that repair damaged tissues
1. (10b) Humoral immunity is carried out by • Killer T Cells • Lymphocytes • Antibodies • macrophages
2. (10b) In the figure below the red bacterium represents a • Antigen or pathogen • Antibody • Killer T Cell • Antigen binding site E
3. (10b) Which of the following is the function of antibodies in the immune response? • Antibodies produce antibiotics. • Antibodies attach to antigens and attract phagocytes which engulf & destroy the antigen. • Antibodies produce interferon.
4. (10c) When a person receives a vaccine, his or her body creates a memory that • Receives antibodies against a specific pathogen • Creates plasma cells that can produce antibodies against that specific pathogen. • Has polio antibodies in the blood • Has antipolio killer T cells in blood
5. 10B Antibodies fight infections by A. Preventing Viruses from replicating B. Killing infected cells C. Helping leucocytes identify pathogens D. Growing green mold that stops bacterial growth