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3.1.6. L.O: to explain how ?? work to define herd immunity to explain why the ‘flu ?? is changed annually Starter: Immunity Crossword of keywords so far!. The History of Vaccinations. Watch the video and answer the following questions: When was Edward Jenner born?
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3.1.6 L.O: to explain how ?? work to define herd immunity to explain why the ‘flu ?? is changed annually Starter: Immunity Crossword of keywords so far!
The History of Vaccinations Watch the video and answer the following questions: When was Edward Jenner born? What was the cow called? What disease did the milkmaids have that made them immune to smallpox? How old was the boy he experimented on? Summarise his experiment http://www.bbc.co.uk/learningzone/clips/edward-jenner-the-discovery-of-smallpox-vaccine/2456.html
How Are Vaccines Made Nowadays? • Dead (inactive) or weakened (attenuated) version of the pathogen L.O.1: How Do Vaccines Work? Activity: On the sheet, arrange the stages into the correct order to explain how vaccines work Challenge: Find 5 words to replace GCSE vocabulary with your new A Level vocabulary!
L.O.1 How Do Vaccines Work? Spot two differences between primary and secondary response!
L.O.1 How Do Vaccines Work? Higher concentration of antibodies produced Faster (steeper gradient)
L.O.3 Why Is the ‘Flu Vaccine Changed Annually? Read the NHS information sheet to answer the following questions: • What month of year does the ‘flu vaccine start being researched? When is it then produced? • How many strains are placed into the vaccine? • Why isn’t strain C placed into the vaccine? • Who shouldn’t have the vaccine incase of allergic reactions? (think from the information given) • Why can you still get ‘flu even if you’ve had the vaccine?
Antigenic Drift vs Antigenic Shift Because viruses have RNA not DNA, they mutate more often, causing their surface antigens to change shape. Drift – antigens change slowly and only slightly Shift – antigens change completely and suddenly = chaos!!
Swine Flu! http://www.youtube.com/watch?v=lFl3FRNpU4E