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Diabetes Products and Services. First Draft: 03, 2007. Client Brief. Summarize the science and scientific developments in the diabetes area Track patents and emerging technologies for solutions to help pre-diabetics and diabetics
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Diabetes Products and Services First Draft: 03, 2007
Client Brief • Summarize the science and scientific developments in the diabetes area • Track patents and emerging technologies for solutions to help pre-diabetics and diabetics • Track products and services currently available for diabetics (and pre-diabetics) in the market • Provide ongoing monitoring and updates for developments in the area
Dolcera Approach • Data collection and mining • 1. Scientific and technological trend • data collection • 2. Product categorization • 3. Demographic, market and regional • trend data Scientific knowledge mapping 1. Develop thorough understanding of the science of the condition 2. Map current scientific and product developments on to the knowledge map Continuous updates Idea development 1. Test technical feasibility of ideas 2. Create implementation strategies 3. Develop ideas and make them lab-ready 4. Create excitement for new ideas Trend analysis and new idea generation 1. Correlate technical trends with scientific research results 2. Identify successful compositions 3. Find the white spaces based on scientific data and generate new ideas
Dolcera Approach • The Dolcera team • Collects and categorizes a large amount of data from diverse sources around the world including scientific publications, patents, market surveys, blogs and images • Develops a knowledge map of the science and maps current developments on to the knowledge map • Analyzes the trends and identifies white spaces and innovation opportunities • Generates new ideas based on the trends and helps implement new ideas
Scientific Data Collection • Science and medicine sources • Patent databases worldwide • SCIRUS • Google Scholar • Medline, PubMed, Medscape and other medical databases • Clinical trial data from FDA and commercial agencies • Product formulation and chemical structure sources • Product surveys • Dietary research • STN
Product Categorization • Products existing in the market will be categorized by • Prescription medication • Over-the-counter medication • Foods: natural and synthetic • Food additives • For each category, the following information will be collected • Medication substance or active ingredient • Substance action • Effect of substance on the body • Delivery process (e.g. devices)
Social, Market and Regional Trends • Sociocultural trends • Consumer trend surveys • Dietary trends • Data sources: Google, Flickr and Blogs • Market trends • Market surveys (AC Nielsen etc.) • Data from related markets such as pharmaceutical industry • Branded diet plans • Regional trends • Identify local products, local traits, and local preferences • Traditional products such as herbal medicines • Dietary preferences by geography
Knowledge Map Development • Overview • Types of diabetes • Signs, symptoms, risk factors • Biochemistry • Molecular biology • Metabolic pathways analysis • Hormonal influences • Mechanisms of action • Effect of mature on metabolic pathways and on hormones • Predicted effect of experimental compositions • Potential white spaces
Example of Trends • Mechanism of action of currently available products • Increase insulin • Increase sensitivity to insulin • Delay absorption of glucose • Decrease the amount of glucose released from the liver • Slow gastric emptying • Lower glycemic index
Whitespace Analysis Example • Current areas of focus • Medication • Diet regulation • Diet regulation approach • Increase low glycemic substitute for the existing food products and altering the taste and flavor to adjust for the same • Delay glucose absorption by delaying digestion by adding more soluble fibers in the diet • Use low Glycemic Index (GI) substitutes • Hypothesize methods to decrease the GI of common food products
Idea Implementation Strategy • Dolcera team will provide • List of compositions and food products • Provide patents and publications to support new ideas • Develop the “virtual products” that could be marketed • Identify technical and market challenges for the “virtual products”
Interesting findings • Drinking Coffee Helps Lower the Chance of Getting of Type 2 Diabetes - 12-18-2006 • Eating a Diet High in Fiber Helps Prevent Gestational Diabetes - 10-31-2006 • Coffee and Green Tea May Help Prevent Type 2 Diabetes - 05-24-2006
Dolcera Approach • Data collection and mining • 1. Scientific and technological trend • data collection • 2. Product categorization • 3. Demographic, market and regional • trend data Scientific knowledge mapping 1. Develop thorough understanding of the science of the condition 2. Map current scientific and product developments on to the knowledge map Continuous updates Idea development 1. Test technical feasibility of ideas 2. Create implementation strategies 3. Develop ideas and make them lab-ready 4. Create excitement for new ideas Trend analysis and new idea generation 1. Correlate technical trends with scientific research results 2. Identify successful compositions 3. Find the white spaces based on scientific data and generate new ideas
Key ingredient of Oreo cookies • Base cake dough • High fructose corn syrup • Dutch cocoa (processed with alkali) • Pure chocolate liquor • Wheat flour • Niacin • Reduced iron • Thiamin mononitrate [vitamin B1] • Riboflavin [vitamin B2] • Folic acid • Partially hydrogenated soybean oil • Baking soda • Cornstarch • Salt • Soy lecithin (emulsifier) • Vanillin - an artificial flavor
Substitutes for High fructose corn syrup • High fructose corn syrup • Contains 55 percent sucrose, which requires insulin to metabolize. • It has very high glycemic index
Substitutes for wheat flour • Wheat flour • Powdery substance derived by grinding or mashing the whole wheat grain • White flour contains diabetes-causing contaminant alloxanSource
Mitigation - High fructose corn syrup • High fructose corn syrup • Increased consumption of high-fructose corn syrup resulting in depletion of chromium in the body, which is important in helping glucose pass from the bloodstream into the cells
Mitigation – Wheat flour • Wheat flour • Ingredients can be combined with regular wheat four mitigating its adverse effects by lowering glycemic index and slowing digestion