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Inheritance

Inheritance. phenotype = genotype + environmental effects. Phenotype and genotype. The overall appearance of an organism depends on two things:. 1. its genes (inherited characteristics). 2. the effects of the environment in which it lives.

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Inheritance

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  1. Inheritance

  2. phenotype = genotype + environmental effects Phenotype and genotype The overall appearance of an organism depends on two things: 1. its genes (inherited characteristics) 2. the effects of the environment in which it lives. All the observable characteristics of an organism are called its phenotype. The full set of genes of an organism is called its genotype. An organism’s phenotype therefore depends on its genotype plus environmental effects.

  3. What do you know about chromosomes?

  4. Different versions of genes allele for brown eyes allele for blue eyes Chromosomes in a homologous pair contain the same type of genes that code for the same characteristics, such as eye colour. Each chromosome in the pair, however, may have a different version of the gene. For example, the version of a gene on one chromosome may code for browneyes, whereas the version of the gene on the other chromosome may code for blue eyes. Each different version of a gene is called an allele.

  5. Homozygous alleles allele forbrown eyes allele forbrown eyes allele forblue eyes allele forblue eyes If the alleles for a characteristic in a homologous pair are the same, the organism is said to be homozygous for that characteristic. What colour eyes will these homozygous pairs of alleles produce?

  6. Heterozygous alleles ? allele forbrown eyes allele forblue eyes If the alleles for a characteristic in a homologous pair are different, the organism is said to be heterozygous for that characteristic. What colour eyes will this heterozygous pair of alleles produce? The characteristic expressed by heterozygous alleles will depend on which allele is dominant and which allele is recessive.

  7. Dominant or recessive? The phenotype for a particular characteristic depends on which allele is dominant and which allele is recessive. • Dominant alleles are always expressed in a cell’s phenotype. Only one copy of the dominant allele needs to be inherited in order for it to be expressed. Dominant alleles (e.g. brown eyes) are represented by an upper case letter (e.g. ‘B’). • Recessive alleles are only expressed in a cell’s phenotype if there is no dominant allele present. If a dominant allele is present, the effect of the recessive allele is ‘masked’. Recessivealleles (e.g. blueeyes) are represented by a lower case letter (e.g. ‘b’).

  8. What eye colour? allele forbrown eyes allele forblue eyes The genotype for someone with an allele for blue eyes and an allele for brown eyes would be written Bb. The dominant allele (brown eyes) has a capital letter and is written before the recessive allele (blue eyes). So, what colour will the eyes be of an individual who is heterozygous for eye colour? The individual will have browneyes, because the allele for brown eyes masks the allele for blueeyes.

  9. Inheritance terms

  10. Homozygous cross

  11. Heterozygous cross

  12. Finding the genotype For example, the allele for brown fur (B) in mice is dominant over the allele for white fur (w). This means that all white mice must therefore have the genotype . white white But what about individuals that have brown fur? Is their genotype BB or Bw ? For some characteristics, the genotype of a homozygous recessive individual can be determined from their phenotype. A test cross can be used to determine whether an individual is homozygous or heterozygous for a dominant trait.

  13. What is a test cross? During a test cross, an individual with an unknown genotype is crossed with a homozygous recessive individual. The phenotype of the offspring will reveal the unknown genotype. • If all the offspring display the dominant phenotype, then the parent of unknown genotype must be homozygous for the characteristic. • If half the offspring show the dominant phenotype, and half show the recessive phenotype, then the parent must be heterozygous for the characteristic.

  14. Using test crosses to find genotype

  15. Y chromosome X chromosome What are sex chromosomes? Humans cells contain one pair of sex chromosomes,which control gender. • Males have one X andone Y chromosome (XY). • Females have two X chromosomes (XX). Y chromosomes are very small and contain 78 genes, whereasX chromosomes are larger and contain 900–1,200 genes. Because females can only produce X gametes, it is the sperm that determine the sex of the offspring at fertilization.

  16. Boy or girl?

  17. Sex determination on the Y chromosome How does the presence of a Y chromosome cause an embryo to develop into a boy? The development of male sexual characteristics is caused by a single gene on the Y chromosome, called the SRY gene. Embryos contain some ‘bipotential’ cells able to grow into either ovaries or testes. The SRY gene causes these cells to form testes. If a Y chromosome is not present, these cells develop into ovaries and the embryo is female, which is the ‘default setting’ for a human embryo.

  18. The life and work of Gregor Mendel

  19. Monohybrid crosses genotype phenotype homozygous dominant homozygous recessive heterozygous The type of experiment that Mendel carried out, investigating just a single characteristic, is called a monohybrid cross. There are two alleles controlling pea shape. This means there are three possible genotypes that the plants could inherit, leading to two possible phenotypes. SS smooth ww wrinkly Sw smooth The likelihood of a trait being produced during a monohybrid cross can be mapped out using a Punnett Square.

  20. What are Punnett Squares?

  21. Expressing outcomes There are a number of ways of expressing the outcomes of genetic crosses. “The chickens are white or brown in a ratio of 3:1.” As a ratio: “75% of the chickens are white and 25% are brown.” As a percentage: As a probability: “The probability of a chicken being white is 0.75, or 3 in 4.”

  22. Monohybrid cross questions

  23. Glossary

  24. Anagrams

  25. Multiple-choice quiz

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