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Intellectual Merit

Cell-Responsive Biomaterials as Tissue Engineering Scaffolds Elizabeth M. Cosgriff -Hernandez , Texas Engineering Experiment Station, DMR 0907067. MMP-2 Enzyme. Intellectual Merit

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Intellectual Merit

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  1. Cell-Responsive Biomaterials as Tissue Engineering ScaffoldsElizabeth M. Cosgriff-Hernandez, Texas Engineering Experiment Station, DMR 0907067 MMP-2 Enzyme • Intellectual Merit • The goal of this project is to develop a tissue engineered ligament graft that will support the injured knee while the body is guided to grow a new ligament. TISSUE ENGINEERING PARADIGM Engineered Ligament Grafts Injured Tissue Healthy Tissue Elastomers with cell-responsive degradation Biomaterial Scaffold These new hybrid materials combine what the body knows how to do with natural materials with the mechanical properties, availability and tunability of synthetic materials. TISSUE REPAIR http://www.dimec.polito.it Bioactive Cues Cells http://stemcelldoc.wordpress.com/2009/02/ http://upload.wikimedia.org Scaffold Cells

  2. Cell-Responsive Biomaterials as Tissue Engineering ScaffoldsElizabeth M. Cosgriff-Hernandez,Texas Engineering Experiment Station, DMR 0907067 Using nature to design better biomaterials BROADER IMPACTS • undergraduate research opportunities for under-represented groups; • Trainees include female students from • Texas A&M Prairie View and • Texas Lutheran University • (2) interdisciplinary training in biomaterials that will prepare undergraduate and graduate participants for future careers; • (3) integration of research into curriculum

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