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12. 10. 8. 6. [BMP9] ng/ml. 4. 2. 0. Healthy donors. HHT donors. Fig 4. A. 2. Serum. Plasma. Luciferase activity (arbitrary unit). 1. 0. Untreated. Donor 1. Donor 2. Donor 3. Donor 4. B. Pooled human serum concentration = 7.5 ± 0.6 ng/ml. 2. Luciferase activity
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12 10 8 6 [BMP9] ng/ml 4 2 0 Healthy donors HHT donors Fig 4 A 2 Serum Plasma Luciferase activity (arbitrary unit) 1 0 Untreated Donor 1 Donor 2 Donor 3 Donor 4 B Pooled human serum concentration = 7.5 ± 0.6 ng/ml 2 Luciferase activity (arbitrary unit) 1 0.3% = 21 pg/ml 0.1% = 8 pg/ml [BMP9] pg/ml 0 10 20 30 40 50 C