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Passende Bildauswahl !

Training. Passende Bildauswahl !. Essential nutrients for your health. What is a Food Supplement?. Contents. Introduction Product Information Key Benefits Posology & Ingredients Recommendations Target Group Vitamin D deficiency 7.1 Vitamin D deficiency and diseases

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Passende Bildauswahl !

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  1. Training Passende Bildauswahl! Essential nutrients for your health

  2. What is a Food Supplement?

  3. Contents • Introduction • Product Information • Key Benefits • Posology & Ingredients • Recommendations • Target Group • Vitamin D deficiency • 7.1 Vitamin D deficiencyanddiseases • 7.2 Osteomalacia & Osteoporosis • 7.3 Rickets • GoodtoKnow • Complementary Treatment

  4. 1. Introduction • Vitamin D has a special position among all vitamins as it is the only vitamin that can be synthesized from the body itself by means of sunlight. • Dependent on the time you spent outside, the body produces round about 80 - 90 % of the required vitamin D, the rest has to be supplied orally. • It is involved in various metabolic processes: • maintenance of normal bones • role in the process of cell division • normal function of the immune system • maintenance of a normal muscle function • normal absorption / utilization of calcium and phosphorus Vitamin D

  5. 1. Introduction Vitamin D metabolism The body‘s vitamin D3 supply is maintained by • Vitamin D synthesis • Induced by UV-B radiation • Up to 80-90 % are build in the skin • Depending on: • Exogenous supply of food • Ergocalciferol (Vitamin D2) made by plants • Cholecalciferol (Vitamin D3) product of animal-based food (Cholecalciferol) (Calcidiol) (Calcitriol) Vitamin D3 is more efficacious at raising serum 25(OH)D concentrations in comparison to vitamin D2.

  6. 1. Introduction A global representation of vitamin D status in healthy populations Vitamin D status in children 1-18 years Vitamin D status in adults > 18 years Source: Wahl, D.A. et al. 2012 A global representationofvitamin D status in healthypopulations. International OsteoporosisFoundationand National OsteoporosisFoundation < 30 nmol/L associated with vitamin D deficiency, leading to rickets in infants and osteomalacia in adults. [1 nmol/L = 0,4 ng/mL]

  7. 2. Product Information For normal bones, muscles and a normal immune system

  8. 2. Product Information For normal bones, muscles and a normal immune system

  9. 3. Key Benefits • Two dosages for different target groups Vitamin D3 for infants and toddlers Vitamin D3 for adults • For healthy muscles, bones, teeth and a healthy immune system • Easy administration for infants and children – 1 tablet per day • Rickets prevention for infants • Osteomalacia and Osteoporosis prevention for elderly people • Complementary treatment with calcium active

  10. 4. Posology & Ingredients INGREDIENTS INTAKE The recommended intake is 1 tablet per day with plenty of fluid. • RECOMMENDATIONS FOR INFANTS AND TODDLERS • Let the tablet dissolve on a spoonful of water and give this to the infant. • Ideally the tablet should be taken orally and during a meal. • AGE RECOMMENDATION • 500 I.E of vitamin D per day - starting after the first days of life for a term of 1-1,5 years • 500 I.E of vitamin D per day if there is an insufficient sunlight exposure above the age of 2

  11. 5. Recommendations Vitamin D Recommendations - German Nutrition Society https://www.dge.de/wissenschaft/referenzwerte/vitamin-d/ Recommended Daily Allowances (RDAs) for Vitamin D Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academy Press, 2010

  12. 6. Target Group Infantsandchildren Olderpeopleover 65 years People who do not get enough direct sun exposure (especially in autumn and winter) Dark-skinnedpeople Vegansandpersonswith a specialnutrientneed Obesepeoplewith a BMI ≥ 30

  13. 6. Target Group VITAMIN D SUPPLY FOR Infantsandchildren • Vitamin D requirements cannot ordinarily be met by human milk alone. • Vitamin D content of human milk is related to the mother‘s vitamin D status. RECOMMENDATION from American Association of Paediatrics: Exclusively and partially breastfed infants must be supplemented with 400 I.U. of vitamin D per day.

  14. 6. Target Group VITAMIN D SUPPLY FOR Vegansandpersonswith a specialnutrientneed People who do not get enough direct sun exposure (especially in autumnandwinter) Olderpeopleover 65 years • Women who wear long robes and head coverings for religious reasons. • Homebound individuals • People with occupations that limit sun exposure. •  Unlikeliness to obtain adequate • vitamin D from sunlight. Risk of an insufficient oral administration. • Their skin cannot synthesize vitamin D as efficiently. • They are likely to spend more time indoors. • They may have inadequate intakes of the vitamin.

  15. 6. Target Group VITAMIN D SUPPLY FOR Dark-skinnedpeople • Larger amounts of the pigment melanin in the epidermal layer: • Darker skin • Reduced capacity to absorb much UV-B-radiation • Reduced capacity to produce vitamin D from sunlight • Impaired Vitamin D synthesis

  16. 6. Target Group VITAMIN D SUPPLY FOR Obesepeoplewith a BMI ≥ 30 • A body mass index ≥ 30 is associated with lower serum 25(OH)D levels compared with non-obese individuals. • Obese people may need larger than usual intakes of vitamin D to achieve 25(OH)D levels comparable to those of normal weight. • Obesity does not affect skin's capacity to synthesize vitamin D directly, but: • Greater amounts of subcutaneous fat • Increased storage of the fat soluble vitamin • Alteration of its release into the circulation.

  17. 7. Vitamin D deficiency • According to Harvard University, an estimated 1 billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency. • Incidence of vitamin D deficiency for children and adults around the globe: < 20 ng/ml generally considered inadequate for bone and overall health in healthy individuals [1nmol/L = 0,4 ng/mL] Reportedincidenceofvitamin D deficiencydefinedas a 25(OH)D < 20 ng/mLaroundtheglobeincludingAustralia (AU), Canada (CA), China (CH), India (IN), Korea (KR), Malaysia (MA), Middle East (ME), Mongolia (MO), New Zealand (NZ), North Africa (NA), Northern Europe (NE), United States (USA). [Holick, M. F. et al. 2012 97(4):1153-1158 Guidelines for Preventing and Treating Vitamin D Deficiency and Insufficiency Revisited Journal of clinical endocrinology & metabolism]

  18. A vitamin D deficiency can occur when usual intake is lower than recommended levels over time exposure to sunlight is limited the kidneys can not convert 25(OH)D to its active form absorption of vitamin D from the digestive tract is inadequate Classical Vitamin D Deficiency Diseases Adults soft bones (osteomalacia) fragile bones (osteoporosis) Children rickets (a failure of bone tissue to properly mineralize) soft bones and skeletal deformities 7.1 Vitamin D deficiency and diseases

  19. 7.2 Osteomalacia & Osteoporosis • Osteomalacia & Osteoporosis • Osteomalacia refers to a softening of the bones and results from a defect in the bone-building process. • Osteoporosis is a disease in which the density and quality of bone are reduced. • As bones become more porous and fragile, the risk of fracture is greatly increased. • The balance between bone resorption and deposition changes with age→ osteoporosis can develop • “Around the world, 1 in 3 women and 1 in 5 men are at risk of an osteoporotic fracture”

  20. 7.2 Osteomalacia & Osteoporosis

  21. 7.3 Rickets • Definition • Vitamin D promotes the absorption of calcium and phosphorus from the gastrointestinal tract. • A deficiency of vitamin D makes it difficult to maintain proper calcium and phosphorus levels in the bones, which can cause rickets. • Risk factors • Age (3-36 month old children) • Exclusive breast feedingwithout supplemental vitamin D • Premature birth • Dark skin Skeletal deformities bowlegs Bone pain Impaired growth Muscle cramps

  22. 8. Good to know Upper limits of Vitamin D • Vitamin D toxicity can cause: • Weight loss • Polyuria • Heart arrhythmia • Raise levels of calcium -> vascular and tissue calcification

  23. 8. Good to know Vitamin D – Good to know Vitamin D3 is NOT recommended for People who suffer from hypercalcemia and or hypercalciuria People who suffer from renal insufficiency Vitamin D may increase the risk of hardening of the arteries in people with serious kidney disease This medications can influence the effect of vitamin D Anticonvulsants Barbiturate (sleeping pills) Glucocorticoids • Triamcinolone (Triam-Denk) • Cortisone • Prednisone • Dexamethasone

  24. 9. Complementary Treatment INDICATION: Bone Health + + + Glucocorticoids Zoledro-Denk Triamcinolone(Triam-Denk) Cortisone Prednisone Dexamethasone • Beneficial to the maintenance of bones, teeth and contributes to a normal muscle function • Significant benefit in osteoporosis as well as other conditions causing bone loss. • Strong inhibitor of osteoclastic bone resorption. • Calcium and vitamin D supplementation for all patients beginning glucocorticoid therapy.

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