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Brainstorming II

Brainstorming II. PSYC 674.101. Topics. Nutritional Neuroscience The “self” effect and evolution Stress and cognitive performance Your ideas…. Multiple levels of organization. Behavior and Cognition. Systems and Circuits. Synapses and Neurons. Genes and Molecules.

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Brainstorming II

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  1. Brainstorming II PSYC 674.101

  2. Topics • Nutritional Neuroscience • The “self” effect and evolution • Stress and cognitive performance • Your ideas…

  3. Multiple levels of organization Behavior and Cognition Systems and Circuits Synapses and Neurons Genes and Molecules

  4. Free radicals: ROSany species capable of independent existence that contains one or more unpaired electrons • hydroxyl radicals • lipid oxyl or peroxyl radicals • singlet oxygen • peroxinitrite free radicals "steal" electrons from the lipids in cell membranes, resulting in cell damage.

  5. Antioxidantsmolecules capable of slowing or preventing the oxidation of other molecules • Vitamin C and E • Various enzymes • Catalase • Superoxide dismutase • Peroxidases

  6. The “hot” antioxidants • Polyphenols – plant derived chemicals containing more than one phenol group • Flavonoids – secondary metabolites (not directly involved in growth and development but may contribute to long-term survival and fecundity). • Proanthocyanin, Procyanidinwas discovered in 1936 by Jacques Masquelier and called vitamin P (associated with the color in fruits and bitter taste of seeds).

  7. can procyanidins improve cognition? • Red wine • Tea • Cocoa • Berry fruit Presumably through antioxidant activity but other mechanisms related to signal transduction are possible.

  8. The wine diethttp://www.telegraph.co.uk/global/main.jhtml?view=DETAILS&grid=&xml=/global/2006/11/27/hwinediet27.xmlnaked scientist segment…

  9. Cocoa may be better than wine and tea

  10. Comparison of cocoa products

  11. Comparison of Cocoa products

  12. Stawberries improved hippocampal-based place learning, blueberries improved striatal-based reversal learning

  13. Gogi (wolf) berries

  14. ORAC measures

  15. The “self effect” Julian Keenan http://www.wnyc.org/shows/radiolab/season1_2005.html Seeing oneself (with the right hemisphere) in computer-generated morphs…. Perhaps one evolutionary advantage is to “see” oneself in real morphs that are a 50/50 genetic combination of two people, aiding in paternal identification.

  16. Stress effects Is there a sex difference in the “half-life of the ANS”? Would a psychologically-induced stressor influence learning performance? Robert Sapolsky on Radio Lab Where am I http://www.wnyc.org/shows/radiolab/episodes/2006/05/05 (3:38 – phantom limbs segment) Stress http://www.wnyc.org/shows/radiolab/episodes/2005/02/11 (15:00 - )

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