1 / 44

Enzyme Catalysis

Enzyme Catalysis. SBS017 Basic Biochemistry Dr John Puddefoot J.R.Puddefoot@qmul.ac.uk. Learning objectives Lecture 11. You should be able to use Lineweaver -Burk plots to calculate KM and Vmax You will be able to describe competitive,

tuan
Download Presentation

Enzyme Catalysis

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Enzyme Catalysis SBS017 Basic Biochemistry Dr John Puddefoot J.R.Puddefoot@qmul.ac.uk

  2. Learning objectives Lecture 11 • You should be able to use Lineweaver-Burk plots to calculate KM and Vmax • You will be able to describe competitive, uncompetitive and non-competitive inhibitors and how they alter enzyme kinetics • You should understand the terms Allosteric and Cooperative regulation in relation to enzymes

  3. Michaelis-Menten Reminder V is the velocity (or rate) of reaction [S] is the substrate concentration Vmax is the maximal velocity of the reaction KM is the Michaelis constant ([S] at Vmax/2)

  4. K+1[E][S] = k-1 + k2[ES]

  5. App

More Related