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No more broken hearts

No more broken hearts. Presented by: Jeffrey Avila Janae Gonzales Burt Matthews. Quantitative Trait Loci Analysis for Plasma HDL-Cholesterol Concentrations and Atherosclerosis Susceptibility Between Inbred Mouse Strains C57BL/6J and 129S1/ SvImJ

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No more broken hearts

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  1. No more broken hearts Presented by: Jeffrey Avila Janae Gonzales Burt Matthews Quantitative Trait Loci Analysis for Plasma HDL-Cholesterol Concentrations and Atherosclerosis Susceptibility Between Inbred Mouse Strains C57BL/6J and 129S1/SvImJ Arterioscler. Thromb. Vasc. Biol. 2004;24;161-166 Naoki Ishimoriet.al.

  2. QTL • What is it?

  3. QTL • What is it? • What does it tell us?

  4. QTL • What is it? • What does it tell us? • Why is it important?

  5. Overview of study • B6X129

  6. Overview of study • B6X129 • 294 F2 Progeny Females

  7. Overview of study • B6X129 • 294 F2 Progeny Females • High Fat Diet

  8. Overview of study • B6X129 • 294 F2 Progeny Females • High Fat Diet • Identify regions on chromosomes using QTL analysis

  9. Phenotypic Measurements

  10. QTL Analysis

  11. Relevance • 6 loci HDL + 5 Loci atherosclerosis suseptability identified • The Future • Lipoproteins • Medications

  12. Ways to increase my HDL levels • Exercise • Increase intake of Omega 3 fatty acids • Eat Onions

  13. A special thanks to…. • Randy Von Smith • Tobias Beckwith • Dr. Brook Milligan • NMSU RISE Program

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