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Figure 7

p65 16 ASGPYVEIIE QPKQRGMRFR YKCEGRSAGS IPGRRSTDTT KTHPTIKING YTGPGTVRIS p50 40 ADGPYLQILE QPKQRGFRFR YVCEGPSHGG LPGASSEKNK KSYPQVKICN YVGPAKVIVQ p65 76 LVTKDPPHRP HPHELVGKDC RDGFYEAELC PDRCIHSFQN LGIQCVKKRD LEQAISQRIQ

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  1. p65 16 ASGPYVEIIE QPKQRGMRFR YKCEGRSAGS IPGRRSTDTT KTHPTIKING YTGPGTVRIS p50 40 ADGPYLQILE QPKQRGFRFR YVCEGPSHGG LPGASSEKNK KSYPQVKICN YVGPAKVIVQ p65 76 LVTKDPPHRP HPHELVGKDC RDGFYEAELC PDRCIHSFQN LGIQCVKKRD LEQAISQRIQ p50 100 LVTNGKNIHL HAHSLVGKHC EDGICTVTAG PKDMVVGFAN LGILHVTKKK VFETLEARMT p65 136 T----NNNP- ---------- ---------- -------FQV PIEEQRGDYD LNAVRLCFQV p50 160 EACIRGYNPG LLVHPDLAYL QAEGGGDRQL GDREKELIRQ AALQQTKEMD LSVVRLMFTA p65 164 TVRDPSGR-P LRLPPVLSHP IFDNRAPNTA ELKICRVNRN SGSCLGGDEI FLLCDKVQKE p50 220 FLPDSTGSFT RRLEPVVSDA IYDSKAPNAS NLKIVRMDRT AGCVTGGEEI YLLCDKVQKD p65 223 DIEVYF---- -TGPGWEARG SFSQADVHRQ VAIVFRTPPY ADPSLQAPVR VSMQLRRPSD p50 280 DIQIRFYEEE ENGGVWEGFG DFSPTDVHRQ FAIVFKTPKY KDINITKPAS VFVQLRRKSD p65 278 RELSEPMEFQ YLPDTDDRHR IEEKRKRTYE TF 309 p50 340 LETSEPKPFL YYPEIKDKEE VQRKRQKLMP NF 369 A * *** * * ****** *** * *** * * *** * * * ** * ** * Motif 1 *** * * **** * ** * * * *** * * * ** * * * *** * * * ** ** * * * *** *** * * ** ** ******** Motif 2 ** * * ** * * ***** **** ** * * * * **** ** Motif 3 * *** * * * * ** * motif 2 C C E279 p65 RHD p50 RHD motif 3 N N κBDNA motif 1 Figure 7 B

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