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VHS- Gattaca - theme of the future ?

VHS- Gattaca - theme of the future ?. DVD- Cracking the Code- DeCode and Iceland.

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VHS- Gattaca - theme of the future ?

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  1. VHS-Gattaca- theme of the future? DVD- Cracking the Code- DeCode and Iceland

  2. Introduction to GeneticsKlug 8th EditionPage 2 Interaction between Genetic Technology and SocietyA. Recombinat DNA technology-insulin page 552-553B. Genetically Modified Food and other organisms (GMO’s) page 550-551C. Gene Therapy-treating genetic disorders page 560-561

  3. Page 2 • Controversy in IcelandA. deCODE a biotechnology company may use health, genealogical, and genetic information of 270,000 residents.B. Why did deCODE choose Iceland?Low genetic diversity in the population

  4. Pros/Cons • Successes: ID of genes for various diseases • Problem: Privacy is in jeopardy

  5. Timeline • 1866 Mendel’s work is published • 1886 Advances in microscopes=chromosomes • 1880’s 1890’s Mitosis/meiosis • 1900 Correns confirms Mendel’s work • early1900’s Sutton and Boveri-Chromosome Theory of Inheritance • Early 1900’s Mutations discoveries led to gene mapping • 1920’s-1940’s Avery, McLeod, McCarty –DNA carries information • 1952-Watson and Crick-double helix

  6. MendelMendelianGenetics • Mendel is the starting point for Genetics (the study of heredity and variation) • 1860’s used garden peas • Identified patterns of inheritance • His work was ignored until Correns in 1900’s confirmed his work • Genes (units of inheritance)occur in pairs and control traits

  7. Mendel and Meiosis • Chromosome numbers in sexual reproduction • Diploid number (2n)- 46 for humans • Homologous chromosomes – one set from Mom and one set from Dad (23 each for humans) • Haploid number (n)- 23 for humans

  8. Genes + Chromosomes • Sutton and Boveri –Chromosome Theory of Inheritance = genes are carried on chromosomes • Fruity Fly studies led to discoveries: • Terms: Mutation (inherited change ingene) Allele (alternate forms of a gene) Phenotype (observable features of genes)

  9. DNA or Protein? • Until 1940’s proteins were thought to be the source of genetic material • Proteins are abundant in the cell and are diverse in structure and function BUT • Fruit Flies, bacteria, and viruses led to the discovery that DNA

  10. DNA + RNA • Alphabets (Genetic Code) • DNA is made of nucleotides (A,T, G, C) • RNA is made of nucleotides (A, U, G, C) • Watson and Crick-double helix with complimentary relationships • A-T(U) G-C • Transcription- DNA to RNA • Central Dogma • of Genetics • Translation- RNA to protein

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