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POLLEN AERO ALLERGENS AND THE CLIMATE IN MEDITERRANEAN REGION OF TURKEY AND ALLERGEN SENSITIVITY IN ALLERGIC RHINOCONJUNCTIVITIS AND ALLERGIC ASTHMA PATIENTS. Arzu Didem YALCIN.MD Internal Medicine, Allergy and Clinical Immunology.
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POLLEN AERO ALLERGENS AND THE CLIMATE IN MEDITERRANEAN REGION OF TURKEY AND ALLERGEN SENSITIVITY IN ALLERGIC RHINOCONJUNCTIVITIS AND ALLERGIC ASTHMA PATIENTS Arzu Didem YALCIN.MD Internal Medicine, Allergy and Clinical Immunology
In this study, we evaluated the profiles of allergic rhino-conjunctivitis and asthma patients annually in Antalya, with aclimate and pollination features typical for a mediterranean coastal city in Turkey • Theprevalences of asthma, allergicrhinitisandallergiceyediseaseweredetected as 8.2%, 10.8% and 7.5% respectively in Antalya, thesouthcoast of Turkey. Inthisstudy, evaluated in allergicrhino-conjunctivitisandasthmapatients
The total and specific IgE levels were made by fluoroenzyme immunoassay method via use of ImmunoCAP kit. Fordermal prick tests Alyostal ST-IR standard allergen extracts were used. 866 of 2862 patients who had allergic rhinoconjunctivitis and asthma were enrolled in the study due to having high total IgE levels in blood conducted at the Allergy- Immunology Unit. Allergen-spesific subcutaneous immunotherapy was given 626 of 866 patients
A questionnaire taking the latest literature data into consideration, were used during the study. These data were oriented to determine the socio-demographic characteristics including the age, gender, place of living, past medical history, diseases that they had, beginning and duration of the symptoms, irritants and allergens that exacerbating the disease and the smoking status.
EnvironmentalFactor Genetic Factor Atopy (CytokineDysregulation) Allergen Pollutant chemical Infection…ect Developmental Component PERSISTENT WHEEZING ASTHMA
RESULTS Of the 866 patients studied, 66.1 % were females and the largest age groups for the diagnosis whom had higher than 100 kU/L total IgE levels and allergen-spesific IgE positivity is the 30-39 ages (23.4 %), as shown in table I. 92.8 % of all patients lived in the city center. Skin prick test performed mostly on May (17.6 %) 16.3 % of the cases were active smokers. Among these cases 40.7 % had increased symptoms with cigarette smoke both in active and passive smoking conditions. There is also a significantly higher SPT positivity rate to trees, mold and epithelium allergens among the smokers.
All the SPT results were given in table II. In our study 52.8 % of the cases had sensitivity for cockroaches. In the study group, the SPT positivity rate to cockroaches increased by age. And this increase was statistically different. The detection of cockroaches in the house had no effect on the results of SPT.
Thank you ARZU DIDEM YALCIN Prof. Dr. H. HüseyinPolat, MD:Cumhuriyet University, Faculty of Medicine, Department of Public Health, 58140 Sivas, Turkey Saime BASARAN, Msc Atıl Bısgın, MD. Prof. Dr. Reginald M GORCZYNSKI, MD, PhD: Division of Cellular & Molecular Biology, Toronto Hospital, University Health Network, Toronto, ON, Canada.REYHAN, RAHİME, HALE, BÜLENT