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口腔診斷學

口腔診斷學. Intraoral brown, bluish and black conditions. 口腔棕色、藍色、黑色疾病. 陳玉昆副教授 : 高雄醫學大學 口腔病理科 07-3121101~2755 yukkwa@kmu.edu.tw. 學 習 目 標. Understanding: 1. Intraoral brown, bluish and black conditions. 參考資料. References:.

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口腔診斷學

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  1. 口腔診斷學 Intraoral brown, bluish and black conditions 口腔棕色、藍色、黑色疾病 陳玉昆副教授: 高雄醫學大學 口腔病理科 07-3121101~2755 yukkwa@kmu.edu.tw

  2. 學 習 目 標 Understanding: 1. Intraoral brown, bluish and black conditions

  3. 參考資料 References: • Kaohsiung Medical University, Oral Pathology Department • Cawson RA: Oral Diseases. 3rd Ed., pp. 11.2-11.10 • Cawson RA: Oral Diseases. 3rd Ed., pp. 11.12 • Cawson RA: Oral Diseases. 3rd Ed., pp. 11.13 • AFIP (American air-force institute of pathology)

  4. Melanin Blood Ref. 1

  5. Brownish, Blackish Pigmented Lesions Exogenous Endogenous Hairy tongue Localized pigmented Endocrine disorder

  6. Tyrosinase Melanocyte Stimulating Hormone Intraoral brown and black conditions Ref. 2

  7. Intraoral brown and black conditions Normal Lentigo simplex Junctional activity Compound nevus Intramucosal nevus Blue nevus Ref. 2

  8. Intraoral brown and black conditions Intramucosal nevus Intraoral Cutaneous Compound nevus Junctional activity Limina propria Refs. 1, 2

  9. Intraoral brown and black conditions Melanophage Pigmented basal keratinocyte Oral Melanotic Macule Epithelium Pigmented basal cell Refs. 1, 2

  10. Intraoral brown and black conditions Amalgam restoration Amalgam retrograde filling Amalgam Tatto Refs. 1, 3

  11. Intraoral brown and black conditions Graphite Tatto Ref. 1

  12. Intraoral brown and black conditions Hairy Tongue Ref. 1

  13. Early Changes of Melanoma • Appear recently • Change in degree of pigmentation • Bleeding or ulceration • Rapid growth (in size or elevated) Refs. 1, 2

  14. Melanoma Ref. 1

  15. Melanoma Ref. 1

  16. Melanoma Ref. 1

  17. Melanoma Ref. 1

  18. Melanoma Immunohistochemical staining of HMB-45 (A) and S-100 (B) revealed diffuse positivity in the tumor cells. Ref. 1

  19. Von Reclinghausen’s disease of skin multiple neurofibroma Cafa-Au-Lait-spot Ref. 5

  20. Cafa-Au-Lait-spot Ref. 1

  21. Addison’s Disease Pituitary Gland product ACTH Cause adrenal produce Gluco-cortisoid (Hydrocortisone) Into Blood circulation Ref. 4

  22. Bluish black macules Intestinal polyp Peutz-Jeghers Syndrome Skin pigment but not oral tends fade with age Refs. 1

  23. Hemangioma Mucocele Hematoma Eruption cyst Bluish Lesions Ref. 1

  24. Varicoses Ref. 1

  25. Mucoepidermoid Carcinoma Ref. 1

  26. SUMMARY Knowing how to differentiate brown, bluish & black oral conditions

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