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Mechanical Ventilation Management. RC 270. Flowrate. Check and adjust (if necessary) on each vent check Meet patient’s inspiratory demand while maintaining I:E Ratio Optimize V/Q Decrease W.O.B. Don’t be afraid to increase flowrate !. Managing PCO2. Math Mechanical Deadspace
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Flowrate • Check and adjust (if necessary) on each vent check • Meet patient’s inspiratory demand while maintaining I:E Ratio • Optimize V/Q • Decrease W.O.B. • Don’t be afraid to increase flowrate!
Managing PCO2 • Math • Mechanical Deadspace • IMV
Math Management of PCO2 • Ve and PaCO2 are inversely proportional • When one changes, the other changes in the opposite direction
Mathematical Method Current (Ve x PaCO2) =Desired(Ve X PaCO2) Use algebra to solve for desired variable
Desired PaCO2 • Usually the one that normalizes ph • Use Siggard-Andersen Nomogram
Setting New Ve • If increasing Ve, increase Vt or rate • Increasing Vt is best • If decreasing Ve, decrease Vt or rate • If possible, decrease rate before Vt (why?)
Example A patient is on A/C CMV with the following settings: FIO2=40%, Vt=600ml, rate =16. ABGs on these settings are: ph= 7.49 PaCO2=30mmhg, PO2=80mmhg, HCO3=23 Find the Ve that will increase PaCO2 and bring the ph to 7.40 1. Find desired PaCO2 using Siggard-Andersen nomogram. 2. Calculate present Ve. 3. Use the formula to determine the new Ve.
Mechanical Deadspace • Patient rebreathes exhaled CO2 • Corrugated flex tubing is added between the ventilator wye and the patient’s airway connection
Intermittent Mandatory Ventilation (IMV) is an excellent way to control PaCO2 The Ve from the ventilator can be titrated with the patient’s spontaneous Ve to achieved a desired PaCO2
Managing PaO2 • Use a-A ratios to predict new PaO2 and new FIO2 • If increasing the FIO2 is not increasing the PaO2, it may be time for CPAP/PEEP
Note: Vd/VT does not change rapidly. Except: Pulmonary embolism