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Determining Properties of Wound Dressings for Negative Pressure Wound Therapy

Determining Properties of Wound Dressings for Negative Pressure Wound Therapy. Lora Aboulmouna, Lisa Lewicki, Ryan Frye. What is NPWT?.

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Determining Properties of Wound Dressings for Negative Pressure Wound Therapy

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  1. Determining Properties of Wound Dressings for Negative Pressure Wound Therapy Lora Aboulmouna, Lisa Lewicki, Ryan Frye

  2. What is NPWT? The application of sub-atmospheric pressure to a sealed wound for the purpose of removing fluid and stimulating a cellular response through the mechanical stretching of wound tissue. • Process: • Material inserted into wound bed • Sealant drape • Fluid drain tube • Vacuum Applied • -50 to -120 mmHg

  3. Pioneer Technology • Aims to discover and create solutions in the healthcare community beginning with advancements in wound care while bridging the gap between healthcare technology and nature • Green healthcare • Discover the benefits of Sorbact and likelihood of commercial success • Mentor: Josh Smith, Vice President of Pioneer Technology • Advisor: Dr. Jack Fisher, Associate Clinical Professor of Plastic Surgery at Vanderbilt University

  4. Wound Dressings KCI Foam Sorbact Gauze

  5. Project Goals • To determine • Material resistance • Flow rate • Pressure gradient • Saturation points of the three materials in a negative pressure environment. • Build a model that provides a controlled environment

  6. Equating the Materials • Procedure: • Obtained three materials with equal masses • Measured water displacement in a graduated cylinder of each sample • Mass and volume were used to determine the density of each material

  7. Preliminary Experiment: Material Behavior in NP Environment • Used skin analog in mold to simulate wound bed • Inserted appropriate material amount • Covered with sealant drape • Applied pressure of 180 mmHg • Observed material compression

  8. Results of Preliminary Experiment • All materials compressed under negative pressure

  9. Design Setup Clinical Pressure Ranges: • -50 to -120 mm Hg Bernoulli’s Principle: • Height of water • Fluid velocity • Vacuum Pressure • Density • Head losses • Pipe P = -180 mm Hg h Q

  10. Design Obstacles • Resistance of tubing • Flow meter range accuracy (o.4 to 40 mL/min) • Small flow rates may cause readings to not be significantly different • All flow travels through materials • Varying Pressure

  11. Future Directions • Obtain accurate flow measurements • Awaiting shipment of proper flow meter • Test flow while varying pressure • Test saturation • Weigh materials before and after saturation

  12. References • Borgquist O, Ingemansson R, Malmsjö M. Wound edge microvascular blood flow during negative pressure wound therapy: examining the effects of pressuresfrom -10 to -175 mmHg. PlastReconstrSurg In press. • Ljungh, A, N Yanagisawa, and T Wadström. "Using the principle of hydrophobic interaction to bind and remove wound bacteria." Journal of Wound Care 15.4 (2006): n. pag. Web. 6 Nov 2010. • Smith, Jan, and Peter Robertsson. Method for Dressing a Wound. , 2010. Web. 27 Oct 2010. <http://www.google.com/patents/about?id=ApHVAAAAEBAJ&dq=sorbact> • "Science Behind the Therapy — KCI." Science Behind The Therapy. Web. <http://www.kci1.com/KCI1/sciencebehindthetherapy>.

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