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PERSONALIZED MEDICINE

PERSONALIZED MEDICINE. What is Personalized Medicine?. Information-based healthcare Person-by-person: high content, resolution & fidelity Ushered in by the sequencing of human genomes Enhanced by new biological knowledge “Right drug, right patient, right dose, right time”

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PERSONALIZED MEDICINE

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  1. PERSONALIZED MEDICINE

  2. What is Personalized Medicine? • Information-based healthcare • Person-by-person: high content, resolution & fidelity • Ushered in by the sequencing of human genomes • Enhanced by new biological knowledge • “Right drug, right patient, right dose, right time” • But NOT limited to management of therapy

  3. Overall Goals • Improve outcomes • Disease care • Health care • Reduce costs

  4. How? • Disease care • Target medicines precisely (“pharmacogenomics”) • Administer medicines safely (“toxicogenomics”) • Health care • Predict disease susceptibility • Prevent disease • Detect early onset of disease • Preempt disease progression

  5. How? • Because Health-care trumps Disease-care • Create a healthier population • Shift more responsibility for care to the individual • Reduce overall “healthcare” costs?

  6. HEALTH personalized MEDICINE

  7. “pH”

  8. What are potential disadvantages? • Greater costs of diagnostics/biomarkers • Smaller patient markets for therapeutics • Need to track individual health information • Necessity for accelerated HIT • Diagnoses without treatments • Re-education of healthcare professionals • Distraction from other $ saving opportunities

  9. As the train is leaving the station… Does California Government have a role In the ”Personalized Health Rush”?

  10. If so, what? What priorities? How to create a recommended plan?

  11. What priorities? • Economics & reimbursement • Short-term vs. long-term perspective • Micro-economics vs. macro-economics • Regulation & Policy development • Privacy & Non-discrimination • Redundancies & confusions • Unintended consequences • Health Information Technology • Encouraging innovation • Educating & training • Integration and implementation

  12. Task Force Leaders • Macroeconomics: Richard Levy • Regulation: William D. Young • Kathy Hibbs • HIT: Ramesh Rao

  13. Next Step? • Complete the Funding

  14. -Steven E. Brenner

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