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ICU Protocols Memphis VA Medical Center. G. Umberto Meduri, M.D. W. Andrew Bell, Pharm.D., BCPS. The ICU Team . ICU Attending Pulmonary and Critical Care Fellow Internal Medicine Resident Medicine Interns Medicine Students ICU Pharmacist Pharmacist Resident Critical Care Nurse
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ICU Protocols Memphis VA Medical Center G. Umberto Meduri, M.D. W. Andrew Bell, Pharm.D., BCPS
The ICU Team • ICU Attending • Pulmonary and Critical Care Fellow • Internal Medicine Resident • Medicine Interns • Medicine Students • ICU Pharmacist • Pharmacist Resident • Critical Care Nurse • Respiratory Therapist • Nutritionist, Physical Therapist, Palliative Care
ICU Protocols Antibiotic treatment of pneumonia Antibiotic treatment for other infections Fluid resuscitation and ScvO2-guided therapy Vasopressors Mechanical ventilation Sedation and analgesia Glucose control Gastrointestinal and thromboembolic prophylaxis Weaning from mechanical ventilation Recombinant human activated protein C (rhAPC) Prolonged glucocorticoid treatment in patients with shock Prolonged glucocorticoid treatment in pts with severe ARDS
Guidelines • ATS / IDSA Pneumonia Guidelines • 2007 Community-acquired pneumonia • 2005 Health care associated pneumonia • Surviving Sepsis Campaign 2008 • SCCM 2002 Analgesia, Sedation, & Neuromuscular Blockade Guidelines • ASHP 1999 Stress Ulcer Prophylaxis Guidelines • Chest 2008 DVT Prophylaxis Guidelines
[continued] ScvO2 = central venous oxygen saturation
Health Care Associated Pneumonia YES Nursing home Hospitalized last 90 days Within last 30 days Hemo dialysis Home wound care YES IV Rx CAP with Risks factors for Pseudomonas aeruginosa Bronchiectasis Structural lung disease No Chronic glucocorticoid use Repeated antibiotics
Gastrointestinal Prophylaxis • All patients enrolled in the study should receive stress ulcer prophylaxis (SUP) with either a H2 antagonist or PPI AJHP 1999; 56: 347-379
Thromboembolic Prophylaxis LMWH = Low molecular weight heparin