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Gene Expression. DNA vs. RNA. Making Proteins. Polypeptides Unedited Editing occurs in one of two places Transcriptional Post translational. Transcriptional Editing. TATA Box Tells RNA polymerase where to begin transcribing. Transcriptional Editing. Transcription Introns are removed
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Making Proteins • Polypeptides • Unedited • Editing occurs in one of two places • Transcriptional • Post translational
Transcriptional Editing • TATA Box • Tells RNA polymerase where to begin transcribing
Transcriptional Editing • Transcription • Introns are removed • Exons remain and get translated • mRNA is formed from exons • (Yes the name seems rather backwards!)
Making Proteins • Post translational • Many different things can happen • Removal of portions • Alteration of functional groups on polypeptide • Glutamic acid can become selenated • Alters folding patterns
The Central Dogma of Biology DNA mRNA Polypeptide
What does it mean? • Are we only a product of our genes? • What is purely genetic? • What is purely environmental?