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干细胞研究及其临床应用

干细胞研究及其临床应用. 组织胚胎学教研室 李秋明. 1 Introduction. 2 A pplication. 3 Challengers Forward. 4 Conclusion. Introduction. 胚胎干细胞 （ embryonic stem cells, ESCs ）. 成体干细胞 （ adult/tissue-specific stem cells, ASCs ）. 成体干细胞 （ adult/tissue-specific stem cells, ASCs ）.

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干细胞研究及其临床应用

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  1. 干细胞研究及其临床应用 组织胚胎学教研室 李秋明

  2. 1 Introduction 2 Application 3 Challengers Forward 4 Conclusion

  3. Introduction 胚胎干细胞 （embryonic stem cells, ESCs） 成体干细胞 （adult/tissue-specific stem cells, ASCs）

  4. 成体干细胞 （adult/tissue-specific stem cells, ASCs） 胰腺、肝、角膜、骨髓、脂肪、脑、 肌组织、肺、皮肤等处干细胞 肿瘤干细胞（tumor stem cell, TSCs）

  5. 损伤再生 临床应用 (细胞、组织、 器官替代) 退行性疾病 免疫性疾病 肿瘤 其他 Application

  6. 基础研究 人类发育模型 基因操作 药物筛选

  7. 定向诱导分化机制不明确 分离、扩增及鉴定成体干细胞 体外长期培养的安全性 排斥反应、 伦理等 Challengers Forward

  8. 具空间构型及正常生理功能的克隆器官移植 定向诱导或/及基因修饰，经筛选后将所需细胞移植 针对组织类型，直接移植相应的成体干细胞 Conclusion

  9. Thank You !

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