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1 2 H+E H+E 3 4 MHC-I H+E
Figure e-1. Muscle and skin biopsy. 1 – Extensive inflammatory infiltrate within two fascicles, predominantly T lymphocytes, some B lymphocytes. Fiber atrophy and hypertrophy; 2 – regenerating muscle fibers and muscle fiber necrosis; 3 - major histocompatibility complex class 1 (MHC-I): diffuse sarcolemic expression; 4 – diffuse skin fibrosis.