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EDCTP funded HIV clinical studies in SSA

EDCTP funded HIV clinical studies in SSA. Dr Thomas Nyirenda. ICASA 2011 3-8 December 2011, Addis Ababa – Ethiopia – . Presentation lay out. About EDCTP Current geographical coverage of the partnership Remit of clinical trials EDCTP funds

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EDCTP funded HIV clinical studies in SSA

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  1. EDCTP funded HIV clinical studies in SSA Dr Thomas Nyirenda ICASA 2011 3-8 December 2011, Addis Ababa – Ethiopia –

  2. Presentation lay out • About EDCTP • Current geographical coverage of the partnership • Remit of clinical trials EDCTP funds • Funded projects (HIV vaccine, microbicide, MTCT and treatment) • Barriers to conduct of HIV clinical trials in SSA • EDCTP strategy to contribute to resolving the barriers • Successes • Gaps

  3. The partnership (2003 – 2011) EDCTP-EEIG member states • Austria • Belgium • Denmark • France • Germany • Greece • Ireland • Italy • Luxembourg • Netherlands • Norway • Portugal • Spain • Sweden • Switzerland • United Kingdom Sub-Saharan African countries • Benin • Botswana • Burkina Faso • Cameroon • Congo • Cote d’Ivoire • Democratic Republic of Congo • Ethiopia • Gabon • Ghana • Guinea • Guinea-Bissau • Guinea-Conakry • Kenya • Liberia • Madagascar • Malawi • Mali • Mozambique • Namibia • Nigeria • Rwanda • Senegal • South Africa • Sudan • Tanzania • The Gambia • Uganda • Zambia • Zimbabwe

  4. EDCTP Mission To fight poverty sub-Saharan Africa by accelerating the development of new or improved drugs, vaccines and microbicides against HIV/AIDS, malaria and tuberculosis, and to improve generally the quality of research in relation to these diseases • Through equal and effective partnership with Africa and African researchers • Through integration of EU Member States national health research programmes

  5. EDCTP Scope

  6. Vaccine projects

  7. Microbicide projects

  8. PMTCT projects

  9. HIV treatment projects

  10. Barriers to conduct of international stand clinical research in sub-Saharan Africa • Lack of adequate and sustainable research funding • Lack of a critical mass of well trained researchers • Lack of adequate research infrastructure • Lack of enabling environment for research (e.g. poor ethics and regulatory standards) • Isolation of well trained cadres • Lack of sharing of facilities and expertise • Lack of mapping and synergising efforts • Lack of common advocacy • Invisible role of public sector

  11. Future of HIV clinical trials in SSA -The EDCTP strategy

  12. Future of HIV clinical trials in SSA – EDCTP Networks of Excellence Western Africa: WANETAM Project Coordinator: Prof. SoleymaneMboup Website: www.wanetam.org • Burkina Faso • The Gambia • Ghana • Guinea-Bissau • Mali • Nigeria • Senegal • United States Central Africa: CANTAM Project Coordinator: Prof. Francine Ntoumi Website: www.cantam.org • Cameroon • Congo, Republic of the • Gabon • France • Germany Eastern Africa: EACCR Project Coordinator: Dr Pontiano Kaleebu Website: www.eaccr.org • Kenya • Sudan • Ethiopia • Tanzania • Uganda • Germany • Sweden • United Kingdom • United States Southern Africa: TESA Project Coordinator: Dr Alexander Pym Website: www.tesafrica.org • Botswana • Malawi  • Mozambique  • South Africa  • Zambia  • Zimbabwe  • France • Germany • Netherlands • United Kingdom

  13. Success of EDCTP funded projects • Increased scientific knowledge • Infrastructure upgrade • Training and mentorship of African researchers • Networking (N-N, N-S and S-S) • Provision of lessons and practical experience to ethics and regulatory bodies

  14. Making a difference After Before

  15. Success of funded projects • Increased scientific knowledge • Infrastructure upgrade • Training and mentorship of African researchers • Networking (N-N, N-S and S-S) • Provision of lessons and practical experience to ethics and regulatory bodies

  16. Closing persistent gaps • More funding to sustain developed sites is required • More finding for establishment of new sites is required • Linkage of projects to programmes like NoE is required • African governments need to start funding the developed sites and assume ownership • Involvement of private sector needs stimulation

  17. Closing persistent gaps

  18. Thank you http://www.edctp.org

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