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FIGURE, SUPPLEMENTAL DIGITAL CONTENT 1. Antibiotics Initiated (A) and Reasons for Initiation (B) after Implementation of Vancomycin Use Reduction Guideline. (A) Naf +/-, nafcillin/oxacillin alone or with another antibiotic; Vanc +/-, vancomycin alone or with another antibiotic; amp, ampicillin; gent, gentamicin; anaer, clindamycin or metronidazole; Ceph, cephalosporins (1st-4th generation); Fungal, antifungal agents. (B) NEC, necrotizing enterocolitis (Bell Stage 2 or higher); Resp, respiratory; Trach, tracheal; Clx, culture; Abnl, abnormal. (A) (B)