1 / 7

PHC 222 Part(I) Dr. Huda Al Salem

PHC 222 Part(I) Dr. Huda Al Salem. Lecture (4). Factors that affect the affinity. 3- Stereochemistry of the drug. Example 1 : Acetylcholine. 3- Stereochemistry of the drug. Conformation. Configuration. is the spatial arrangement of bonds in a molecule in a permanent geometry.

vern
Download Presentation

PHC 222 Part(I) Dr. Huda Al Salem

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PHC 222Part(I)Dr. Huda Al Salem Lecture (4)

  2. Factors that affect the affinity 3- Stereochemistry of the drug

  3. Example 1: Acetylcholine

  4. 3- Stereochemistry of the drug Conformation Configuration is the spatial arrangement of bonds in a molecule in a permanent geometry. Requirement: can be changed only by breaking bonds is the spatial arrangement of atoms in a molecule that comes from free rotation of atoms around a single chemical bond. Requirement: It occurs without breaking bonds..

  5. 3- Stereochemistry of the drug C` C` C A` A` A B` B` B

  6. Example 2: Norephedrine

  7. Example 3: Labetalol

More Related