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dynGraph

dynGraph. “Don't stop for nobody This time I'll keep my feet on solid ground Now I understand myself when I'm down ”. Interactive visualization of 'factorial planes' integrating numerical indicators…and the beat goes on. Example. PPAR-alpha mice (P. Martin) Individuals: 40 mice

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dynGraph

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  1. dynGraph “Don't stop for nobodyThis time I'll keep my feet on solid groundNow I understand myself when I'm down” Interactive visualization of 'factorial planes' integrating numerical indicators…and the beat goes on

  2. Example • PPAR-alpha mice (P. Martin) • Individuals: 40 mice • 20 wild, 20 PPAR-alpha deficient • 5 diets (dha, efad, lin, ref, tsol) • Variables: • 120 genes • 21 hepatic fatty acids • Objective: to highlight similarities between genes expression and clinical variables

  3. Example • The 5 diets • Dha: DHA is the most abundant essential fatty acid (polyunsaturated fatty acids) in the brain and retina, omega 3 fatty acids • Efad: Essential Fatty Acid Deficient, only saturated fatty acids based on hydrogenated coconut oil • Lin: flax oil, omega 3 fatty acids • Ref: according to the advised nutritional supplies for the French population, 6 omega 6 for 1 omega 3 • Tsol: sunflower oil, essentially omega 6

  4. Example • The peroxisome proliferator-activated receptors (PPARs) are a group of proteins that function as transcription factors regulating the expression of genes. • PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, and protein) of higher organisms.

  5. Main features: data frame & factorial planes • Change the axes • Qualitative and quantitative values-representation • Categories and quantitative variables visual description • Labels edition (move and delete) • Points edition (delete) • Export to png, pdf, svg and emf

  6. Main features: factorial planes • Axes visual description • Quality of representation visual index • Move quickly from one plane to another • PCA, CA, MCA, MFA, AFDM

  7. Data flow rJava FactoMineR raw data

  8. Thanks for your attention And the beat goes on…

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