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ISOQUINOLINE DERIVATIVES

ISOQUINOLINE DERIVATIVES. Kh Sadique Faisal Asst. Lecturer Northern University Bangladesh. Tubocurarine.

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ISOQUINOLINE DERIVATIVES

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  1. ISOQUINOLINE DERIVATIVES KhSadique Faisal Asst. Lecturer Northern University Bangladesh

  2. Tubocurarine • Tubocurarine (also known as D-tubocurarine or DTC) is a skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation. Unlike a number of other related skeletal muscle relaxants, it is now rarely considered clinically to facilitate endotracheal intubation.

  3. Berberine • Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. • uses • Diabetes, dyslipidemias and cardiovascular conditions • Berberine lowers elevated blood total cholesterol, LDL cholesterol, triglycerides

  4. Sanguinarine • Sanguinarine is a quaternary ammonium salt from the group of benzylisoquinoline alkaloids. It is extracted from some plants, including bloodroot (Sanguinariacanadensis) • Numerous published, pre-clinical In Vitro and In Vivo studies have demonstrated that Sanguinarine causes targeted apoptosis in human cancer cells, and recommend future development of Sanguinarine as a potential cancer treatment

  5. Codeine • Codeine or 3-methylmorphine (a natural isomer of methylated morphine) is an opiate used for its analgesic, antitussive, antidiarrheal, antihypertensive, antianxiety, sedative and hypnotic properties, to suppress premature laborcontractions, myocardial infarction, suppress coughing, as well as many other uses

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