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Approach to leucocytosis. Jackie Thomson. LYMPHOID. MYELOID. ACUTE / IMMATURE. MATURE/ CHRONIC. LYMPHOID. IMMATURE. MATURE. MYELOID. B-ALL T-ALL. LYMPHOID. IMMATURE. MATURE. MYELOID. B-ALL T-ALL. LYMPHOID. IMMATURE. MATURE. AML MDS. MYELOID. B-ALL T-ALL. LYMPHOID. CLL
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Approach to leucocytosis Jackie Thomson
MATURE/ CHRONIC
LYMPHOID IMMATURE MATURE MYELOID
B-ALL T-ALL LYMPHOID IMMATURE MATURE MYELOID
B-ALL T-ALL LYMPHOID IMMATURE MATURE AML MDS MYELOID
B-ALL T-ALL LYMPHOID CLL ALL LYMPHOMAS BURKITT LEUKAEMIA MYELOMA IMMATURE MATURE AML MDS MYELOID
B-ALL T-ALL LYMPHOID CLL ALL LYMPHOMAS BURKITT LEUKAEMIA MYELOMA IMMATURE MATURE AML MDS CHRONIC MYELOID LEUKAEMIA ESSENTIAL THROMBOCYTOSIS POLYCYTHEMIA VERA MYELOFIBROSIS MYELOID
Child • Infections • Leukemia most common ALL
Adult • Good history: • Infection • B symptoms • Tierdness • Bleeding • Burning eyes • Skin
adult • FBC • NB look at platelets and HB • Contact the hematologist when you have a clinical suspicion regarding patient • Remember flow cytometry • Fish • Molecular testing
adult • Exam: • Look for spleen/ lymphnodes • Mouth ulcers • Auto immune /artritis • erythromialgia