1 / 1

HMGbox

A. b -catenin bd. HMGbox. TCF4. dnTCF4. N-TCF4. NLS. B. Ls174T N –TCF4. -. -. -. -. +. +. +. +. I. 2. -. -. +. +. Dox. N -TCF4. - Dox. +Dox. Top / Fop. 1. 2. C. N -TCF4. Tet-R. 1. 2. - Dox. Ls174T. + Dox. D. N -TCF4. 1. 2. - Dox. 68 %. 28 %. BrdU FITC.

waite
Download Presentation

HMGbox

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. A b-catenin bd HMGbox TCF4 dnTCF4 N-TCF4 NLS B Ls174T N –TCF4 - - - - + + + + I 2 - - + + Dox N -TCF4 - Dox +Dox Top / Fop 1 2 C N -TCF4 Tet-R 1 2 - Dox Ls174T + Dox D N -TCF4 1 2 - Dox 68 % 28 % BrdU FITC 36 % 10 % + Dox Propidium Iodide Ls174T N -TCF4 E Down-regulated Up-regulated I 2 I 2 Dox MUC2 BMP-4 c-MYC CAII FABP-L EPHB3 p21CIP1/WAF1 NRP/B 28s 28s 18s 18s

More Related