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Introduction

Introduction. Hemochromatosis Alzheimer's Constant company A global, evolutionary Macarena I t’s not only good for X-Men DNA is history Somewhere in your genetic code is the tale of every plague, every predator, every parasite, and every planetary upheaval your ancestors mangled to survive.

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Introduction

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  1. Introduction • Hemochromatosis • Alzheimer's • Constant company • A global, evolutionary Macarena • It’s not only good for X-Men • DNA is history • Somewhere in your genetic code is the tale of every plague, every predator, every parasite, and every planetary upheaval your ancestors mangled to survive

  2. Chapter 1 • Hemochromatosis is inherited—and the gene for it is very common in certain populations • Iron Locking- Vivkings- founder’s effect • Bubonic plague: 1/3 to ½= 25 million people • People with Hemochromatosis are less susceptible? • Increase in European populations every time the disease resurfaced over the ensuing three hundred years • Evolutionary bottleneck • We did ask for it! • Cystic fibrosis and TB

  3. Chapter 3 • Sunlight: Vitamin D and Folic Acid • Skin Color • Dark to protect folate • Light to manufacture vitamin D • Inuit • High cholesterol to increase vitamin D • ACHOO • Alcohol flush response (alcohol vs. tea) • Slave trade and salt- evolutionary bottleneck • Environmentally dependent • What happens when the environment changes (moves or migrations?)

  4. Chapter 4 • The fava bean- Where’s there folklore smoke, there’s medical fire • Free radicals and enzyme deficiency • Fava cultivation and favism • >400 million • Fruit, botanical birth control & poison • JBS Haldane • SCD • Favism • Malaria • Why cultivate what can kill you?

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