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Polymeric nanoparticles in drug delivery : overcoming barriers to reach the market. A drug d elivery c ompany. Polymeric nanoparticles. Business model. Nanomedicine Clinical Investigations. Commercial Nanomedicine Products. Nanomedicine application in development. Licensing.
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Polymericnanoparticles in drugdelivery: overcoming barriers to reach the market VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
A drug delivery company VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Polymeric nanoparticles VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Business model NanomedicineClinicalInvestigations CommercialNanomedicineProducts Nanomedicineapplication in development Licensing Co-development LABORATORY MARKET VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Key points to overcome the barrier VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Polymeric nanotechnology for drug delivery Superior product benefit Increased bioavailability Controlled release Enhanced solubility Robust stability profile VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Favorable conditions for collaboration Intellectual property rights until 2032 PCT/EP2012/056900 Nanoparticles comprising esters of poly (methyl vinyl ether-co-maleic anhydride) and uses thereof PCT/EP2013/052795 Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Smooth regulatory pathway All excipients are GRAS listed Very well known excipients: water, ethanol , propylene glycol... Widely used in a diverse range of pharmaceutical formulations GRAS: Generally Recognized as Safe VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Easy and cost-effective production No volatile organic solvents Avoids the use of special equipment and techniques Production using standard processes of solution preparation Low cost of goods ensures excellent profit margin VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Successful case 1: minoxidil VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Successful case 1: minoxidil VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Successful case 2: mucosal vaccination VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Successful case 2: mucosal vaccination Mucosal immunization with antigens-loaded nanoparticles induces long lasting immunity VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
To take home VIII Jornadas de Aplicaciones Industriales de la Nanotecnología
Contact details • Ricardo Palacios, PhD, MBA • Business Development Director • rpalacios@bionanoplus.com www.bionanoplus.com Plaza Ceín, 5 Nave 14B | Polígono industrial Mocholí 31110 Noaín – Navarra | SPAIN LET US HELP YOU IN… • Increasing bioavailability of hydrophobic or hydrophilic molecules • Improving stability • Increasing drug solubility • PK modification • Controlled releasing of molecules • Enhancing of residence time • Drug targeting • Drug isolation from incompatible excipients VIII Jornadas de Aplicaciones Industriales de la Nanotecnología