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A legnagyobb epidemiológiai vizsgálat a táplálkozás és a krónikus betegségek összefüggésében. A Kína T anulmány. Heath Trends since 1950. Overweight, obesity, NIDDM Dementias (AD = ‘Type 3 diabetes’) Hypertension: 25% of US adults (USDA 2000) Pre-hypertension: 30% of US adults (AR)MD
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A legnagyobb epidemiológiai vizsgálat a táplálkozás és a krónikus betegségek összefüggésében A Kína Tanulmány
Heath Trends since 1950 • Overweight, obesity, NIDDM • Dementias (AD = ‘Type 3 diabetes’) • Hypertension: 25% of US adults (USDA 2000) • Pre-hypertension: 30% of US adults • (AR)MD • Eosinophilic GI disorders; ‘explosive growth’ (Noel et al ’04) • Non-tobacco related cancers: 100% increases • lymphoma, leukaemia, melanoma, germ cell tumours in teens & young adults (NCIC ‘04) • ADD/ADHD/dysphasia/dyspraxia (U. Washington ’05)
Rising health costs WHO 2000
Rising health costs 2006 19.7 WHO 2000
Iatrogenic Deaths (USA) • Total > 250,000 / year (3rd leading c.o.d) • 7,000 - medication errors (in hospitals) • 20,000 - other hospital errors • 80,000 - hospital-acquired infections • 106,000 - adverse effects of drugs • 12,000 - unnecessary surgery Starfield B et al: JAMA 284:483-5 2000
Reduced energy expenditure 1940 50 60 70 80 DoH ’98, USDA ’02, NIH ’03, NCHS ‘04
Obesogenic culture (AHA ’03) Avge US adult sedentary 8 hours / day, < 2,000 steps / day (NYS Public Health Assocn ‘05) Amish 16,000 steps /day: obesity 9% women, 0% men (Bassett et al ’04)
Positive energy balance 1940 50 60 70 80 DoH ’98, USDA ’02, NIH ’03, NCHS ‘04
The Western Diet • High fat & refined carbs • High calorific density • Low micronutrient / calorie ratios Type B malnutrition • Foods which are energy-dense & low fibre: do not satiate ‘passive over-eating’ (‘up-sizing’) overweight
Hardee’s ‘Monster Thickburger’ 1420 calories, 107 g fat: $5.49
Real World Pyramid Pepsi Pizza
Dietary shift 1950 - 1997 • World consumption of calories from meat increased 36% • “ “ calories from vegetable oil increased 46.2% • US & EU “ sugars and starches increased 35% • World consumption of calories from complex carbohydrates fell 38% • UK consumption of fresh vegetables fell 24% • Per capita income closely related to energy availability • In countries where per capita income increased, so did average caloric consumption • High-income nations derive most energy from sugars and fats – poorer nations catching up rapidly (USDA, Worldwatch, FSA, Drewnowski ’77 & ‘03)
Nutrition in children & Adolescents • Most commonly eaten foods: bread, savory snacks, crisps, chips, boiled, mashed and jacket potatoes, biscuits, chocolate confectionery. • 5 veg / fruit per day: < 50% • 0 fruit per day: 20 - 30% • 0 veg per day: 4% • Dieting: 15% girls, 3% boys National Diet & Nutrition Survey 2000
DIETARY SHIFT • Flavonoids 75% • Vit C 50-60% • Omega-3 50% • Methyl groups 95% • Carotenoids 40% • Phospholipids 50% since 1900 • Selenium 50% ” 1960 (UK) • Prebiotic fiber 50% ” 1960 (Fr) • Sterols 66% ” 1960 (SA) since Stone Age
C E A B1 B2 NiacinFolate B6 B12 --------------------------------------------------------------------- 37 68 55 32 31 27 34 54 17 % % Depletion Vitamins (USDA 1997)
Fat - but starving • W.H.O. ‘02: ‘Globally, overweight greater health problem than underweight.’ • W.H.O./F.A.O ’03: ‘Poor diet the major cause of degenerative disease’. • U.N. ’06: Overweight but malnourished • 40-60%hospital admissions malnourished(1-3) • 25-30% malnourished in the community J Nutr Hlth Ageing 3:133-139, ‘99 • > 3.6 million malnourished in UK (BANT ’07)
MALNUTRITION TYPE A MICRONUTRIENTS CALORIES
MALNUTRITION TYPE A TYPE B MICRONUTRIENTS CALORIES