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Les facteurs qui affectent la collaboration des petites entreprises de biotech / Factors that affect collaboration of small biotech firms. Catherine Beaudry École Polytechnique de Montréal. Alliances et partenariats : un défi pour les biotech
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Les facteurs qui affectent la collaboration des petites entreprises de biotech/Factorsthat affect collaboration of smallbiotechfirms Catherine Beaudry École Polytechnique de Montréal Alliances et partenariats : un défi pour les biotech Alliances and partnerships: a challenge for biotechs CIRANO, 19 septembre 2008
Collaboration in Canada • In 2004-2005, 52.6% of biotech firms participated to at least one collaborative alliance • Large (> 150 employees): 59.6% (10% of the sample) • Medium (50-150 employees): 56.6% (15% of the sample) • Small (<50 employees):50.9 % (75% of the sample) • What are the most common types of collaborative arrangements? • With which partners do SMEs cooperate? • Are SMEs different from larger firms in terms of the number of collaboration arrangements to which they participate? • Do specific characteristics of a firm influence how much it collaborates? negative binomial regressions Factorsthat affect collaboration of smallbiotechfirms
Why collaborate? • To survive! (Oliver 2004) • Access to financial resources • R&D: long and expensive • Difficult for small firms that depend on angels, venture capital, debt, grants, alliances • Access to human capital • Lack of skilled labour is one of the principal reason to collaborate • Access to knowledge and competences • Rather than developping within the firm • Learning networks are the source of innovation (Powell et al. 1996) Factorsthat affect collaboration of smallbiotechfirms
Data • Statistics Canada Biotechnology use and development surveys, 1999, 2001, 2003, 2005 • Binary variable – collaboration yes/no • Count variable – number of collaborative arrangement Factorsthat affect collaboration of smallbiotechfirms
Evolution of collaboration Creditcrunch in 2001 reduction in collaboration in 2003 Factorsthat affect collaboration of smallbiotechfirms
With whom and why? Factorsthat affect collaboration of smallbiotechfirms
With whom and why? Decrease over 4 years of collaboration with public institutions (increase in 2005) Factorsthat affect collaboration of smallbiotechfirms
With whom and why? Decrease over 4 years of knowledge–related collaboration (increase in 2005) Factorsthat affect collaboration of smallbiotechfirms
With whom and why? Following the credit crunch of 2001, firms decreased dramatically their alliances with other firms for knowledge purposes, but maintained their commercialization partnerships Resurgence of knowledge-related alliances in 2004-5 Factorsthat affect collaboration of smallbiotechfirms
Collaboration in general (negative binomial regressions) Factorsthat affect collaboration of smallbiotechfirms
Collaboration by type Factorsthat affect collaboration of smallbiotechfirms
Collaboration by partner Factorsthat affect collaboration of smallbiotechfirms
Collaboration for knowledge Factorsthat affect collaboration of smallbiotechfirms
Collaboration for commercialization Factorsthat affect collaboration of smallbiotechfirms
Conclusions • Younger firms collaborate in a greater number of alliances • Spinoffs in general are more likely to have a greater number of collaborative arrangements • The number of products and processes has a strong and positive influence on the extent of collaboration • Patents needed for commercialization but not for other types of alliances (not in terms of numbers) • Contracting out is no substitute for alliances • Contracting in makes use of the lab space that would otherwise be used for collaboration • Firms with more export revenues are further along the market path and require less to collaborate Factorsthat affect collaboration of smallbiotechfirms
Further research • Follow the firms over the years • Linked database at Statistics Canada (4 linked surveys) • Find out which firms survive and which firms disappear • Discover what are the success factors for firm survival and success • Link the databases with the science-base network • Find the influence of the geographical and technological space on industrial innovation Factorsthat affect collaboration of smallbiotechfirms
Thank youQuestions? Here is some of the work being done at École Polytechnique de Montréal Hairy roots of the Madagascar periwinkle (Catharanthus roseus) Factorsthat affect collaboration of smallbiotechfirms