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LSEC

A. 140. CCN3/NOV. 120. 100. 80. rel. mRNA expression. 60. C. 40. M. KC. LSEC. pMF. HSC. Hepatocytes. 20. 0. 2d. 2d. 0d. 0d. sec. 0d. 2d. 3d. 0d. 1d. 2d. 3d. 1d. 3d. 5d. 7d. 8d. 2d. 4d. HSC. MFB. CCN3/NOV (40 cycles). 4.5. CCN2/CTGF. 4. 3.5. GAPDH. 3.

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LSEC

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  1. A 140 CCN3/NOV 120 100 80 rel. mRNA expression 60 C 40 M KC LSEC pMF HSC Hepatocytes 20 0 2d 2d 0d 0d sec. 0d 2d 3d 0d 1d 2d 3d 1d 3d 5d 7d 8d 2d 4d HSC MFB CCN3/NOV (40 cycles) 4.5 CCN2/CTGF 4 3.5 GAPDH 3 2.5 rel. mRNA expression 2 1.5 D 1 0.5 0 1d 3d 5d 7d 8d 2d 4d HSC MFB 7.0 -SMA 6.0 5.0 4.0 rel. mRNA expression CCN3/NOV (green) ED2 (red) 3.0 2.0 1.0 0 1d 3d 5d 7d 8d 2d 4d HSC MFB B  p = 0.02 35 CCN2/CTGF 30  p = 0.04 merge DAPI (blue) 25 20 relative mRNA expression 15 10 5 0 0d 1d 2d 3d Hepatocyte

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