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BONE TUMOURS. DR Valentine Mandizvidza. BONE TUMOURS. 1. Benign tumours 2. Malignant tumours Further classified as 1.Primary 2.Secondary. Bone Tumours. Further classified according to tissue of origin - bone-forming( osteogenic ) - cartilage-forming ( chondrogenic )
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BONE TUMOURS DR Valentine Mandizvidza
BONE TUMOURS 1. Benign tumours 2. Malignant tumours Further classified as 1.Primary 2.Secondary
Bone Tumours Further classified according to tissue of origin - bone-forming(osteogenic) - cartilage-forming (chondrogenic) - fibrous (fibrogenic) -vascular
Role of Imaging • Detection 2. Diagnosis 3. Surgical staging 4. follow-up
Imaging 40-50% trabecular bone distraction before an area of lucency is demonstrated Cortical destruction is far more easily seen Difficult to detect in areas such as the spine and pelvis
Clinical History and Examination DIAGNOSIS OF BONE TUMOURS Used in conjuction with radiographic findings to come up with differential diagnoses
Clinical History and Examination Age Previous medical history Family history • Ollier’s disease (multiple enchondromas) Ethnic/ geographic origin • KS(HIV), Burkitt’s lymphoma(tropical Africa)
Radiographic Assessment 1. Site in skeleton WHICH BONE IS AFFECTED? 2. Location in bone WHERE IN THE BONE IS THE LESION? • OS (metaphysis or metadiaphysis • ES (metaphysis or diaphysis) • Epiphyseal lesion in a child (chondroblastoma, langerhans cell histiocytosis, abcess) 3. Pattern of bone destruction WHAT IS THE TUMOUR DOING TO THE BONE? 4. Periosteal reaction WHAT FORM IF ANY IS PRESENT? 5. Matrix WHAT TYPE OF MATRIX MINERALIZATION?
Radiographic AssessmentPATTERN OF BONE DESTRUCTION • Fast/ Slow growth • Permeative or moth eaten/ well defined margins Lytic, expansile& well defined ABC
Radiographic AssessmentPERIOSTEAL REACTION Shell Lamellar Interrupted Combined
Radiographic Assessment MATRIX Osteiod, cloud to ivory-like Cartilage is stippled, popcorn in appearance
American Joint Commission for Cancer (AJCC)Classification System for Bone Tumours
BENIGN BONE TUMOURS ABC GCT SBC
Malignant bone forming tumours OSTEOSARCOMA
. CHONDROSARCOMA
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