1 / 10

Parkinson’s Disease

By Katelyn Chaimson and Sean Guyot. Parkinson’s Disease. Origin. First described as “shaking palsy” by physician Galen in AD 175 Later named after London Dr. James Parkinson in 1817 after his study of the disease. What is Parkinson’s Disease?.

wilma-mcmahon
Download Presentation

Parkinson’s Disease

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. By Katelyn Chaimson and Sean Guyot Parkinson’s Disease

  2. Origin • First described as “shaking palsy” by physician Galen in AD 175 • Later named after London Dr. James Parkinson in 1817 after his study of the disease

  3. What is Parkinson’s Disease? • Neurological Disease that affects neurons in the brain causing the body to tremble and movement to be impaired • Affects over 1,000,000 Americans today • One and a half times more likely to affect men • Commonly occurs after age 60 or older • Second most common neurodegenerative disorder • Affects every 13 in 100,000 people/60,000 new diagnosis per year

  4. Types • Adult-onset Parkinson's disease is most common • Early-onset Parkinson's disease (onset between 21-40 years) • Juvenile-onset Parkinson's disease (onset before age 21) rarest

  5. Causes • No one cause • Environmental Exposures • Nerve cells in substantianigra become impaired or die • These cells produce dopamine which produces smooth physical movements • Genetic/Hereditary • Caused by mutations in the LRRK2, PARK2, PARK7, PINK1, or SNCA gene(familial) • Alterations to GBA and UCHL1 genes heighten risk of development

  6. Symptoms • Depression • Dementia(memory loss) • Tremors • Shaking that begins most often in the hands/fingers • Slowed Movement(bradykinesia) • Steps become shorter • Rigid Muscles • Muscles become stiff • Impaired Posture/Balance • Posture becomes slouched • Loss of Natural Movements • Decreased ability to perform unconscious movements • Abnormal Speech/Writing • Speech becomes slurred and writing becomes smaller/more difficult

  7. Treatment • No cure • Treatments suppress harsher symptoms • PT • Increase movement prevents arthritis • Levodopa • Best medication for PD patients • Combined with Carbidopa to reduce side-effects and form Sinemet • Increases dopamine • MAO-B inhibitors • Blocks enzyme that breaks down Levadopa

  8. Prognosis • Life expectancy is generally the same as general population • Both Chronic(persists over time) and Progressive(symptoms worsen over time) • Symptoms differ from person to person • Not directly fatal • Can cause Pneumonia or Fatal Falls

  9. Research • The Michael J. Fox Foundation For Parkinson’s Research • Fox Trial Finder-online database that PD patients can access to find out info on what studies they can be a part of • PPMI-Parkinson’s Progression Marker Initiative; clinical study to discover the biomarkers of PD • Parkinson’s Disease Foundation • founded in 1957, PDF has supported $100 million in research • goal of finding causes, advancing therapies and ending Parkinson's • Connection between ulcers and PD

  10. Works Cited • “Disease and Conditions: Parkinson’s Disease.” Mayo Clinic. Mayo Foundation for Medical Education and Research, 2014. Web. 10 May 2014. • “NINDS Parkinson’s Disease Information Page.” National Institute of Neurological Disorders And Stroke. NIH, 1 May 2014. Web. 10 May 2014. • “Parkinson’s Disease Prognosis.” The Michael J. Fox Foundation For Parkinson’s Research.The Michael J. Fox Foundation, 2014. Web. 9 May 2014. • “Parkinson’s Disease.” MedicineNet.com. MedicineNetInc, 4 Dec 2013. Web. 10 May 2014. • “Understanding Parkinson’s.” Parkinson’s Disease Foundation. Parkinson’s Disease Foundation Inc, 2014. Web. 10 May 2014.

More Related