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Hepatitis A: Epidemiology

Hepatitis A: Epidemiology. Presentation Prepared by: David Spach, MD and Nina Kim, MD Last Updated: May 31, 2011. HEPATITIS A : EPIDEMIOLOGY. Incidence Data. HEPATITIS A : EPIDEMIOLOGY. Acute Hepatitis A: 2011 Case Definition.

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Hepatitis A: Epidemiology

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  1. Hepatitis A: Epidemiology Presentation Prepared by: David Spach, MD and Nina Kim, MDLast Updated: May 31, 2011

  2. HEPATITIS A : EPIDEMIOLOGY Incidence Data

  3. HEPATITIS A : EPIDEMIOLOGY Acute Hepatitis A: 2011 Case Definition • Clinical Case DefinitionAn acute illness with:(a) discrete onset of symptoms and(b) jaundice, dark urine, or elevated ALT levels (ALT > 200 IU/L) • Laboratory Criteria for DiagnosisImmunoglobulin (IgM) antibody to hepatitis A virus (anti-HAV) positive • Case ClassificationConfirmed: meets the clinical case definition and is laboratory confirmed

  4. HEPATITIS A : EPIDEMIOLOGY Incidence of Hepatitis A in U.S., 1980-2008 Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

  5. HEPATITIS A : EPIDEMIOLOGY Incidence of Hepatitis A in U.S., 1980-2008 Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

  6. HEPATITIS A : EPIDEMIOLOGY Incidence of Hepatitis A in U.S., 1980-2008 Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

  7. HEPATITIS A : EPIDEMIOLOGY Impact of Hepatitis A Vaccine on Estimated Total New Hepatitis A Infections in U.S., 1980-2008 2006: ACIP Recommends Universal Childhood Immunization 1996: ACIP Recommends for High-Risk Groups 1999: ACIP Expands Recommendations 1995HAV Vaccine Licensed Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

  8. HEPATITIS A : EPIDEMIOLOGY Reported Hepatitis A, by Age Group and Year, United States, 1990-2004 †ACIP = Advisory Committee for Immunization Practices Source: ACIP. MMWR Recomm Rep. 2006;55(RR-7):1-23.

  9. HEPATITIS A : EPIDEMIOLOGY Rate* of Hepatitis A, by County in United States, 1987-1997 and 2004 *Rate per 100,000 population National Notifiable Disease System Source: ACIP. MMWR Recomm Rep. 2006;55(RR-7):1-23.

  10. HEPATITIS A : EPIDEMIOLOGY Emerging Infections Program, Hepatitis Surveillance Sites, 2005-2007Potential Source of Infection or Risk Factor for Hepatitis A in US IDU = Injection drug useMSM: men who have sex with men Source: Klevens RM, et al. Arch Intern Med. 2010;170:1811-8.

  11. HEPATITIS A : EPIDEMIOLOGY Reported Risk Factors for Hepatitis A Virus Infection Percentage of Risk Factors Among Patients with Acute Hepatitis A Infection Source: CDC. Hepatitis Surveillance Report No. 59;2004.

  12. HEPATITIS A : EPIDEMIOLOGY Prevalence of Antibody to Hepatitis A Virus, by Country, 2006 Source: ACIP. MMWR Recomm Rep. 2006;55(RR-7):1-23.

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