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Complex Inheritance

Complex Inheritance. 2-Locus interactions, Epistasis Sept. 18, 2003. Traits were: Clearly distinguishable pairs of phenotypes Traits appeared in all plants Phenotypes distinguished varieties of peas Traits were “stable” in hybrids and subsequent generations. Mendel’s Traits in Peas.

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Complex Inheritance

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  1. Complex Inheritance 2-Locus interactions, Epistasis Sept. 18, 2003

  2. Traits were: • Clearly distinguishable pairs of phenotypes • Traits appeared in all plants • Phenotypes distinguished varieties of peas • Traits were “stable” in hybrids and subsequent generations Mendel’s Traits in Peas 2-3

  3. Grain Phenotypes in Corn

  4. purple Epistasis in Biochemical Pathways • In Corn, the aleurone pigment is formed by the following pathway. • CRAPr • pc cl1 cl2 red • cc, CIrraapr pr • The endosperm color pathway is: • Y • whiteyellow • yy

  5. genotypic, phenotypic “Monohybrid” -- Independent Segregation alleles areparticulate allelessegregate 2-7

  6. Dihybrid Cross“Complementation” • AAcc X aaCC • (Yellow) (Yellow) • AaCc • (Purple) • When two mutant strains are crossed and the F1 hybrids show normal function, we say that the two strains complement each other, and the mutant alleles are at different loci so they are non-allelic and the loci are non-homologous.

  7. Y Colorless -carotene Vitamin A (retinol) yy Pig Traits (grain nutrition) Endosperm (color) (Corn Traits) Pleiotropy of Y-locusfunction in endosperm

  8. Corn Pig

  9. early intermediate late Developmental Timing of Ac activity is affected by epistatic loci

  10. DNA chip

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