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Congenital anomalies 1993 –2010 Statistical Report 1/2013 in figures Annukka Ritvanen Seija Sirkiä

Congenital anomalies 1993 –2010 Statistical Report 1/2013 in figures Annukka Ritvanen Seija Sirkiä. Congenital anomalies 1993-2010. In 1993–2010, the prevalence of births with major congenital anomalies remained rather stable.

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Congenital anomalies 1993 –2010 Statistical Report 1/2013 in figures Annukka Ritvanen Seija Sirkiä

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  1. Congenital anomalies 1993–2010Statistical Report 1/2013 in figuresAnnukka RitvanenSeija Sirkiä Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL

  2. Congenital anomalies 1993-2010 • In 1993–2010, the prevalence of births with major congenital anomalies remained rather stable. • Annually major anomalies were detected on average in 3,5 per cent of births or in slightly more than 2000 births. • The major periodic variations in the prevalence are associated with the reforms in the Malformation Register activities. The smaller random variation is due to the rarity of congenital anomalies. • There were no significant differences between the data of the various malformation types for 2010 and data for previous years. • During the follow-up period 1993–2010 an average of about 250 pregnancies were terminated annually because of major foetal structural anomalies and chromosomal defects. The number of selective terminations of pregnancy has slowly increased, being about 340 in 2010. Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL

  3. Figure 1. Prevalence of cases with major congenital anomalies (1/10 000 births) in 1993–2010. Miia Artama, projektipäällikkö, Stakes 3 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL

  4. Miia Artama, projektipäällikkö, Stakes 4 Figure 2. Proportion (%) of selective terminations of pregnancy of all cases with major anomalies in 1993–2010. [Selective terminations of pregnancy / (births + selective terminations of pregnancy)]. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 4

  5. Miia Artama, projektipäällikkö, Stakes 5 Figure 3. Prevalence of selective terminations of pregnancy(1/10 000 births)in 1993–2010. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 5

  6. Miia Artama, projektipäällikkö, Stakes 6 Figure 4. Prevalence of cases with major congenital anomalies (1/10 000 births)in the areas of special responsibility of the university hospitals in 1993–2010. The areas of special responsibility of the university central hospitals HUCH =Helsinki and TUCH =Turku and university hospitals TAUH =Tampere, KUH =Kuopio and OUH =Oulu. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 6

  7. Miia Artama, projektipäällikkö, Stakes 7 Figure 5. Proportion (%) of selective terminations of pregnancy performed for foetal abnormalities of all cases with major congenital anomalies in the areas of special responsibility of the university hospitals in 1993–2010. [Selective terminations of pregnancy / (births + selective terminations of pregnancy)]. The areas of responsibility of the university central hospitals HUCH =Helsinki and TUCH =Turku and university hospitals TAUH =Tampere, KUH =Kuopio and OUH =Oulu. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 7

  8. Miia Artama, projektipäällikkö, Stakes 8 Figure 6. Prevalence for anencephaly and spina bifida (1/10 000 births)in 1969–2010. Anencephaly Spina bifida 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 8

  9. Miia Artama, projektipäällikkö, Stakes 9 Figure 7. Proportion (%) of selective terminations of pregnancy of all pregnancies with anencephaly and spina bifida in 1981–2010.[Selective terminations of pregnancy / (births + selective terminations of pregnancy)]. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 9

  10. Miia Artama, projektipäällikkö, Stakes 10 Figure 8. Prevalence for Down syndrome (trisomy 21)(1/10 000 births)in 1993–2010. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 10

  11. Figure 9. Prevalence for Down syndrome (trisomy 21)by maternal age groups (1/10 000 births) in 1993–2010. 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 11

  12. Miia Artama, projektipäällikkö, Stakes 12 Figure 10. Prevalence for Down syndrome (trisomy 21) (1/10 000 births)in 1991–2010; standardised and non-standardised by maternal age groups. 1. 1. Births and selective terminations of pregnancy 2. Births 3. Selective terminations of pregnancy 3. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 12

  13. Miia Artama, projektipäällikkö, Stakes 13 Figure 11. Proportion (%) of selective terminations of pregnancy of all pregnancies with Down syndrome (trisomy 21) in 1993–2010.[Selective terminations of pregnancy / (births + selective terminations of pregnancy)]. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 13

  14. Miia Artama, projektipäällikkö, Stakes 14 Figure 12. Proportion (%) of selective terminations of pregnancy of all pregnancies with Down syndrome (trisomy 21) in 1993–2010 by maternal age groups.[Selective terminations of pregnancy / (births + selective terminations of pregnancy)]. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 14

  15. Miia Artama, projektipäällikkö, Stakes 15 Figure 13. Prevalence for orofacial clefts in births and in births and selective terminations of pregnancy (1/10 000 births) in 1974–2010. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 15

  16. Miia Artama, projektipäällikkö, Stakes 16 Figure 14. Total prevalence (1/10 000 births) for cleft palate (CP) and cleft lip with or without cleft palate (CLP) in 1974–2010. 9.9.2014 9.9.2014 Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL 16

  17. Links • Congenitalanomalies 1993−2010 Statistical Report 1/2013: • www.thl.fi/fi/statistics/congenitalmalformations • www.thl.fi • www.icbdsr.org • www.eurocat-network.eu Statistical Report 1/2013 / Annukka Ritvanen and Seija Sirkiä / Malformation Register / THL

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