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PIG Excretion. What are the cells lining the Proximal convoluted tubule called? (1). What is are the cells lining the Proximal convoluted tubule called?. Epithelial cells. How are substances reabsorbed in the Proximal convoluted tubule? (5).
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What are the cells lining the Proximal convoluted tubule called? (1)
What is are the cells lining the Proximal convoluted tubule called? • Epithelial cells
How are substances reabsorbed in the Proximal convoluted tubule? (5)
How are substances reabsorbed in the Proximal convoluted tubule? • Selective reabsorption • Of glucose and amino acids • By co-transporter proteins • Microvilli provide a large surface area for uptake • Water moves out by osmosis
How is pressure maintained in the glomerulus? • Afferent arteriole is wider than the efferent arteriole leading to • High hydrostatic pressure in glomerulus
Why would happen if someone ate loads of protein in their diet? (4)
Why would happen if someone ate loads of protein in their diet? • More urea produced • More protein broken into amino acids • Increased deamination • More ammonia formed • More ammonia converted to urea • Called the ornithine cycle (ornithine is a name for one of the products and a catalyst that helps in this process)
Why do you need anti-coagulant in dialysis? • So that clots don’t form • While blood is in the machine
Why is no anti-coagulant added to the blood at the end of dialysis? (1)
Why is no anti-coagulant added to the blood at the end of dialysis? • So blood can clot normally after treatment
How do molecules and ions move from the blood into the dialysis fluid? (1)
How do molecules and ions move from the blood into the dialysis fluid? • diffusion
Why does the blood flow in the opposite direction of the dialysis fluid in the machine? (2)
Why does the blood flow in the opposite direction of the dialysis fluid in the machine? • Maintain a diffusion gradient • Allowing maximum removal of waste
Describe the barrier between the glomerulus and Bowman’s capsule? (3)
Describe the barrier between the glomerulus and Bowman’s capsule? • Endothelium: narrow gaps for plasma to pass through • Basement membrane: collagen fibre and glycoprotein mesh • Podocytes: epithelial cells with major processes (finger like projections) and gaps o fluid can pass through
What is filtered out of the blood? • Water • Amino acids • Glucose • Urea • Inorganic ions
How is the permeability of the collecting duct controlled? (5)
How is the permeability of the collecting duct controlled? • Osmoreceptors in hypothalamus lose water by osmosis • They shrink and release ADH • ADH binds to receptors in cells of collecting duct • Aquaporins fuse with cell membrane • More water is reabsorbed
What is the name for the process where fluid passes from the glomerulus into the renal tubule? (1)
What is the name for the process where fluid passes from the glomerulus into the renal tubule? • ultrafiltration
What is the product of glycolysis • pyruvate
Name 2 co-enzymes involved in respiration • NAD and FAD
What are the 4 stages of respiration? • Glycolysis • Link reaction • Krebs cycle • Electron transport chain (oxidative phosphorylation)
Where do the 4 stages of respiration take place? • Glycolysis- cytoplasm • Link reaction- mitochondrial matrix • Krebs cycle- mitochondrial matrix • Electron transport chain- across inner mitochondrial membrane