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Poroma

Poroma. Deba P Sarma, MD Omaha. M 75, right hip. Dark epithelial downgrowths with multiple attachments to the epidermis. And several interconnections. The neoplastic cells are monomorphic, dark.

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Poroma

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  1. Poroma Deba P Sarma, MD Omaha

  2. M 75, right hip

  3. Dark epithelial downgrowths with multiple attachments to the epidermis. And several interconnections. The neoplastic cells are monomorphic, dark.

  4. Foci of ductal luminal differentiation characterized by small ductal spaces surrounded by small epithelial cells and covered by eosinophilic lining towards the lumen

  5. Comment • Poromas is a benign adnexal tumor arising from sweat gland (eccrine and apocrine) duct. • Location: Mostly foot and ahnd. • May be painful. • Poroma are three types: A. Intraepidermal poroma (Hidroacanthoma simlex) B. Intradermal poroma (Dermal duct tumor) C. Poroma (Compound poroma), the most common type

  6. Histology • Poroma shows intraepidermal nests of small monotonous polygonal cells with low mitotic activity. • The tumor cells generally demonstrate direct downward growth into the dermis as interconnected basaloid proliferations. • The intraepidermal nests of basaloid cells are smaller than the adjacent keratinocytes and show intercellular bridges. • There are foci of maturation towards ducts characterized by lumen formation surrounded by eosinophilic material over small epithelial cells. • Differential diagnosis: Basal cell carcinoma, Seborrheic keratosis

  7. Ref: • Sarma DP, Zaman SU, Santos EE, Shehan JM. (2009). Poroma of the hip and buttock. Dermatology Online J 15(5):10. PMID: 19624988 [Pubmed- indexed for MEDLINE].

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